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Intussusception is the invagination of a bowel segment into another immediately adjacent, causing obstruction, and the etiology can be benign, malignant, or idiopathic. The diagnosis may be obtained by ultrasound scans, or computed tomography imaging that can detect characteristics findings. Small bowel obstruction due to intussusception of inverted Meckel's diverticulum is a rare condition that usually constitutes a challenging diagnosis in adulthood. The surgical management in adults is often performed by en bloc resection without reduction attempts. We report a case of CASE REPORTS a middle-aged man with acute intestinal obstruction due to an ileo-ileal intussusception of inverted Meckel's diverticulum with a lipoma that was managed by laparoscopy. Worthy of note is the very scarce number of case reports on this exceeding uncommon association.

ABSTRACT   Objective: To emphasize the increase, in the last decades, in the incidence of kidney diseases and associated comorbidities and, within a wide range of kidney injury triggers, it is important to mention the nephropathies caused by crystal and mineral deposition, considering the often slow, gradual and asymptomatic progression of these disorders. Methods: This is a literature review based on the search for articles related to the topics ‘Crystalluria and renal hypoxia’, in databases such as Pubmed, Bireme, Web of Science and Google Scholar. Results: It can be observed that, of the metabolic processes involved, inflammation and renal hypoxia, which are mutually related, are variables of interest to be considered in this type of injury. Understanding and monitoring the impact of mineral deposition and / or the formation of crystals in the renal parenchyma is an extremely important factor in this context. Conclusion: Mineral imbalance and the urinary saturation of some crystallization promoters, such as oxalate, as well as the inflammation and hypoxemia process, make the kidney environment prone to acute or chronic disorders, possibly due to the disconnected of these variables. Keywords: Oxalate; hypoxia; vascular calcification; renal failure, chronic; COVID-19

Com o aumento expressivo das doenças renais, bem como da litíase renal, a cristalúria tem se destacado como possível desencadeadora de lesões nos rins tendo em vista certas variáveis como exposição ao calor, desidratação, ingestão de bebidas açucaradas durante a reidratação, como resultado de desordens metabólicas e até mesmo em casos de doenças autoimunes. Portanto, o conhecimento dessas partículas e o contexto de seu aparecimento tornou-se de extrema importância na atualidade clínico-diagnóstica. É cada vez mais imprescindível enxergar o conjunto de indícios que podem estar relacionados àquele cristal, observado microscopicamente, que vai desde o histórico laboral do paciente até o consumo de certos alimentos e medicamentos.

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