Introduction:Colonic lipomas are benign tumors of adipose tissue that are often asymptomatic, but they may present with rectal bleeding or obstructive symptoms. These tumors are unique in that they are rarely encountered within the gastrointestinal system and can mimic malignant tumors in appearance. Surgical resection and endoscopic removal of tumors have been shown to be successful in their management.Patient concerns:In this report, we present 3 cases of colonic lipomas, 2 of which are located in the cecum and the other within the sigmoid colon. The presenting symptoms of the patients included abdominal pain, constipation, and dyspepsia.Diagnosis:Patients typically presented with anemia and an elevated C-reactive protein count. Colonoscopic and computerized tomography findings were used for diagnosis.Interventions:Hemicolectomy was performed, depending on the localization, and the pathologic specimens were consistent with lipoma.Outcomes:Surgical resection was curative in all patients. The postoperative period was uneventful in all patients and all patients are symptom-free and alive at 3 years follow-up.Conclusion:Colonic lipomas are benign mesenchymal tumors of the gastrointestinal system with a male predominance and are observed within the fourth to sixth decades of life. Various genetic abnormalities have been reported and they have been linked to the formation of intussusception. The squeeze sign on radiological imaging, cushion sign and tenting sign in colonoscopy, and naked fat sign during pathologic examination is helpful towards reaching a diagnosis. Surgical resection is the treatment of choice but minimally invasive endoscopic approaches have also been shown to be successful.

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Lipomas are benign soft tissue tumours that can occur anywhere on the body and are rarely encountered on the chest. The pathophysiology between soft tissue trauma and lipoma development is not fully understood, and various theories have been presented. We present the case of a violinist with a 40-year occupational history who presented with swelling of the left upper chest wall. The microscopic sample of the resected lipoma showed inflammatory cells with fat necrosis, which are features thought to be involved in the development of a lipoma following soft tissue trauma.

Acute appendicitis is one of the most common abdominal surgical emergencies worldwide. Clinical diagnosis is possible in most of the cases although imaging modalities may become necessary if the diagnosis is uncertain. Appendectomy, preferably the laparoscopic approach, still remains the gold standard treatment to date. The pathophysiology usually includes luminal obstruction by an appendicolith or lymphoid hyperplasia and rarely parasitic infections. In this report, we present an extremely rare case of a patient with diagnosis of bipolar disorder and a history of trichophagia resulting in trichobezoar formation within the appendiceal lümen leading to acute appendicitis.