Background: Anemia due to Iron deficiency is the commonest malnutrition disorder seen throughout the world and in India. It is also responsible for increased incidence of premature births, low birth weight babies and high perinatal mortality. Hence, the present study undertaken to assess efficacy and safety of injectable iron sucrose with oral ferrous ascorbate.Methods: 100 pregnant women, between gestational age 14 and 28 weeks were divided randomly into two groups i.e. group A consists of oral iron, a total of 200 mg of elemental iron per day, two 100mg iron tablets per day and group B consists of iron sucrose at the rate of 200mg on alternate OPD day. Informed consent was taken from each patient.Results: The percentage rise in hemoglobin at fourth and eighth weeks of treatment was statistically significant when compared to the baseline. Statistically significant rise in hemoglobin, PCV and ferritin levels were found at fourth and eighth weeks in IV group when compared to oral group.Conclusions: This study concluded that intravenous iron sucrose is safe and highly efficacious for the treatment of anemia in pregnancy. It restores iron stores more promptly. Iron sucrose therapy is more effective in achieving the optimum results, an increase in hemoglobin concentration, PCV levels and an increase in ferritin levels also. Therefore, it is a suitable alternative to oral iron with minimal side effects in those patients who cannot tolerate oral iron therapy.
Background: Maternal anemia leads to many adverse effects on the fetuses fetal complications. The mechanisms leading to increased morbidity include a decreased oxygen delivery capacity and the dysfunction of enzymes. The aim of this study to relationship between iron status of pregnant mothers and their newborns using a combination of several hematological parameters. Subjects and Methods: A hospital based descriptive type of observational study done on 50 singleton primi pregnant women at term gestation (37-42 weeks) admitted to labour room in government Medical College and general Hospital, Dungarpur (Raj.). General physical examination was done meticulously to assess maternal conditions regarding anemia such as nutritional status, pallor, edema and glossitis. Results: Our study showed that the male to female ratio was 1.28:1. Normal birth weight in baby was seen in 80% of cases. The spearman correlation of hemoglobin concentration was statistical significant in the newborns of mothers with hemoglobin concentration ( 2 = 0.14, 0.50, 0.61 respectively and = 0.0076**, 0.009** & 0.02** respectively). The newborns ferritin level has significant correlation with hemoglobin ( 2= 0.142, <0.001) and ferritin ( 2= 0.253, < 0.001) levels of their mothers. Conclusion: we can conclude that maternal anemia may have an effect on the iron stores of newborns.
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