Lung cancer worldwide is the most common malignancy in men, whereas in women it ranks second. At the same time the lung cancer is the leading cause of cancerrelated death. Today, smoking is considered as the major cause of lung cancer. About 90% of lung cancers in men and 78 % of lung cancers in women may be associated with long-term smoking.A total of 173 patients with histologically confirmed NSCLC and SCLC were included in this prospective-retrospective study. In the study, all patients were divided into two groups: operable ( 117) and inoperable (56). To quantify the association of certain risk factors and the incidence of lung cancer, an odds ratio (OR) 95 % CI was calculated. To determine the level of significance, the value of p <0.05 was taken, and the value of p <0.01 was taken for high significance.The mean age of the group was 60.2 ± 8.7 years, with the youngest patient in the study group aged 31 and the oldest 75 years. There were 80 pensioners (46.25%) and 59 (34,1%) able-bodied patients in the structure of the socioeconomic status. In regard to smoking status, the majority were smokers. The period of smoking was over 20 years and longer; in regard to intensity of smoking they were divided into three groups: smokers with more than 20 years of smoking experience and more than one pack of cigarettes per day -49.13%, smokers with more than 20 years of smoking experience and one pack of cigarettes per day -5.78%, and smokers who smoke more than 20 years but not continuously -15.61%. Occupational exposure was present in 16.18% of the study population, while positive family history was present in 20.81% of patients. Regarding heredity, applying the Chi-square test, we have shown that heredity has a highly significant correlation with the type of cancer reported in both groups.The demographic characteristics of the test are shown to be statistically significant in relation to lung cancer.
Introduction: Scoliosis is a three-dimensional deformity of the spine, which as a pathological condition was known and treated at the time of Hypocrites. Scoliosis is a problem which exists in all countries around the world, especially in the developing ones. In RM, scoliosis among school children at the age of 7-14 is represented by 7.5 %. Objective: To certify the representation of radiologically diagnosed scoliosis among school children in RM, the specific types of scoliosis in relation to age, location, degree of scoliosis according to the angle of deviation of the spine, as well as to define the risk factors for the occurrence. Study Design: Casecontrol study from casual type conducted on children at the age of 7-14. Methods: In order to fulfil the purposes of the research, two groups were formed: examined and control group. Children were divided into three groups according to age: the age of 7-9, 10-12 and 13-14. A questionnaire was also prepared on the basis of recommendations given by SRS. The questionnaire consisted of 15 rules and was intended for parents. Statistical processing was done in Statistics for Windows 8.0. Results: According to gender distribution, scoliosis is more likely to be found in females, 64.49% in comparison to male children. Distribution according to age illustrates that scoliosis is most likely to appear among age groups of 10-12, 58.7%. Juvenile and adolescent scoliosis is much more likely to appear in female children. The connection between the socioeconomical status and scoliosis was also confirmed. Namely, 52.9% of children from average socioeconomical status according to FAS-scale have 2.18 times significantly greater risk of developing scoliosis. Ratio of scoliosis according to the place of living (urban and rural area) is 52.9% : 47.1%. Sitting in front of the computer, physical inactivity, as well as high BMI is a great risk factor for development of scoliosis. The questionnaire also confirmed low level of education among parents regarding this problem, 15.9%. Symmetrical sports prevent scoliosis from developing. Within the examined group of children, the division is made according to the level of scoliosis: mild, medium and severe scoliosis. Most often developed is the double scoliosis 66.87% in comparison to single thoracic 12.32% and lumbar 21.02% deviation. The angle of deviation (Cobb) moves in intervals of 9-78 degrees, with average value of 15.76+8.5. Conclusion: The first research of this type in the country, which gives information of essential significance for improvement and promotion of health, as well as improvement of primary prevention, all aiming to protect child health, and thus creating a healthy society and realization of the Declaration of WHO "Health for everyone in the 21st century".
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