The disease Amlapitta is a frequent presentation in clinical practice. Excess formation of vitiated pitta (Pitta Drava guna vridhi) due improper dietary and lifestyle habits is thought to be the main pathological mechanism behind manifestation of this disease. Classical Ayurvedic formulations like Avipattikar choorna and sutasekhar Rasa are often prescribed in combination for its effective management. The present study was conducted to evaluate the efficacy of both these classical formulation in the management of urdhwaga Amlapitta. The study was a single arm, open clinical trial involving 133 patients of Amlapitta attending the OPD of All India Institute of Ayurveda, New Delhi, India. All patients were screened on the basis of classical clinical findings of Amlapitta and were administered with a combination of sutasekhar rasa (125 mg twice a day orally after principal meals) and Avipattikar choorna (5 g twice a day orally after principal meals) for 04 weeks period. Scoring scale based on classical clinical features of Amlapitta was adopted for the assessment of the disease. Routine pathological tests such as blood, urine, stool, etc. were carried out. During the study, 20 patients dropped out and 113 patients were followed.

Hypertension is a condition in which the arteries have persistently elevated blood pressure. It is considered as the silent killer as most sufferers are asymptomatic. Essential or primary hypertension is considered as the leading contributory cause of death worldwide. Despite good access to care, admittance to lifestyle modification, and the presence of highly efficacious anti-hypertensive therapies, management of hypertension effectively has been a distant reality. Developing innovative and cost-effective solutions to improve hypertension diagnosis and control thus remains a key priority. The present study was conducted to evaluate the efficacy of polyherbal compound M-Sarpagandha Mishran in the management of Essential Hypertension. 41 patients of essential Hypertension (HT) under the age group of 18-70 years without any co-morbid illness, attending the OPD under National Campaign of All India Institute of Ayurveda, New Delhi, India were selected for the study. All patients were screened on the basis of JNC 7 criteria of HT and were administered M-Sarpagandha Mishran for 8 weeks. Blood pressure (BP) was monitored on subsequent follow up visits at 2, 4, 6, and 8 weeks. Change in Diastolic BP (DBP), Systolic BP (SBP) and Mean arterial BP (MBP) was analyzed statistically by paired Student's t-test. During the study, 11 patients dropped out and 30 patients were followed. Paired t test was applied using SPSS software to analyze the data. On first visit the mean SBP, DBP, and MBP was 158.53 + 2.471, 98.37 + 2.203 and 118.43 + 1.558 mm Hg, respectively. After 8 weeks of therapy there was a statistically significant fall in SBP (126.6 + 1.897), DBP (78.37+ 1.264) and MBP (84.43 + 1.268) in mmHg (P value <0.0001) M-Sarpagandha Mishran offers an efficacious and safe combination for the treatment of hypertension.

Psoriasis is a common skin disease which is inflammatory, proliferative, autoimmune, and chronic with relapsing nature. It resembles with Kitibha Kustha roga ofAyurveda which is described asrelapsing disease with dry, rough, discolored skin lesions. This is a case report of psoriasis patientwho was treated conservatively with Kitibha har kashay for 3 months. The assessment of clinical improvement was made, along with the biochemical profiling and photographic analysis. Patient was also instructed to follow the do’s and don’ts of the disease for diet and lifestyle also called pathya and apthya. Parameters that were used to assess the clinical improvement were PASI score, IGA scale and grading of Ayurvedicclinical symptoms of Kitibha.The patient was given the medication prepared from the AyurvedicPharmacy, Faculty of Ayurveda, BHU in ghan form. The crude and prepared drug was standardized from Institute itself and the data of the patient was maintained by regular follow-ups. The cell line study of water extract of Khadir compound was also done to evaluate the proliferative or antiproliferative action by MTT assay. The clinical result have shown that this drug posses a very effective antipsoriatic action that has significantly reduced PASI score to nil and marked improvement in IGA scale, clinical symptoms andphotographic improvement was found. The cell line study by MTT assay has shown the antiproliferative action of Daruharidra (Berberis aristata) that was one of the constituent of Kitibha har kashay.Further study of this drug on psoriasis specific cytokines is needed to be evaluated by biochemical analysis to evaluate its role in breaking the pathology of psoriasis.

Non-healing ulcers or Dushtavrana possess a great challenge to the doctors, as it is a very common problem presented by the patients. It is not only that the patient feels the pain and discomfort but the others who look at the patient, they also feel a lot of discomfort. It creates a very embarrassing situation for the patient in his day to day life. After trying for all the therapies eventually patient looks forward to Ayurvedic system of medicine with a very little ray of hope that here his ulcer may be healed. Fortunately only with the help of Ayurvedic medicines and without any sort of surgical intervention the patient get healed. This article presents the conservative management of non-healing ulcers or Dushtavrana which proved to be a miracle for the patients.

Ayurveda defines human body is made of different gross and subtle channels called srotas. Srotas are the channels through which different elements undergo transformation, transmutation, circulation and transportation. The srotas is an integral part of the body, serving as a route to conduct or convey a substance from one place to other. There are 13 major srotas mentioned. The Srotas or channels which carry Anna or Food is called Annavaha Srotas. Some authorities equate the Annavaha Srotas with the some parts of digestive system or the gastrointestinal tract. Agni, the transformative energy, in the Annavaha srotas digest and transforms the food into components suitable for the body. Impairment of function of agni is root the cause of the disease, which manifest either in Annavaha srotas or other srotas in the body. Thus, correction of agni is the prime in treatment of any disease. Elimination of vitiated doshas by Pancakarma procedure viz Vaman and Virechana has shown to have impact on agni through various guna in the drugs used in these therapy. Sodhana procedures has a significant role in improving the function of agni and restoring the health.