ResumenEn el presente artículo se analizan los cambios y las continuidades en las rutas del flujo de migración de tránsito irregular o no documentada por México. Con base en los registros administrativos del Instituto Nacional de Migración relacionados con los eventos de retención de migrantes que no acreditan su legal estancia en el país, se delinean las posibles rutas de internación, recorrido y salida de la migración centroamericana que se dirige a Estados Unidos. Los resultados advierten sobre la complejidad que ha adquirido este fenómeno como consecuencia de factores asociados a la seguridad, los fenómenos naturales, la violencia y las políticas migratorias en Estados Unidos y México. AbstractThe purposes of this article are plotted and analyzed changes and continuities in the flow paths of migration of undocumented transit spanning through Mexico. Records-based store administration of Instituto Nacional de Migración related events of retention of migrants that not accredit his legal stay in Mexico and through geographical and descriptive analytical method would outline possible routes of admission, tour and flow of undocumented Central American migrants that are directed toward the United States. Results warn about the complexity that it has acquired this migratory phenomenon as a result of factors associated with security, natural phenomena, violence and immigration policies in the United States and Mexico.Palabras clave: migración de tránsito irregular o no documentada, registros administrativos, eventos de retención de migrantes, rutas del flujo de tránsito, rutas de internación, recorrido y salida, migrantes centroamericanos.

Background: To explore the incidence and characteristics of new-onset pain, its impact on quality of life (HRQoL), and to quantify the presence of mood disorders in critically ill COVID-19 survivors. Methods: This is a preliminary report of PAIN-COVID clinical trial (NCT04394169) presenting a descriptive analysis in critical ill COVID 19 survivors one month after hospital discharge. Pain was assed using the Brief Pain Inventory short form, Douleur Neuropathique 4 Questions test and Pain Catastrophizing Scale. Health related quality of life (HRQoL) was evaluated with EQoL-5D/5L and mood disorders with Hospital Anxiety and Depression test (HAD).Results: From May 27th to July 19th 2020, 203 patients were consecutively screened for eligibility and 65 were finally included in this analysis. In 33 (50.8%) patients a new-onset pain was reported: 18 (54.5%) reported clinically significant intense pain, 11 (33.3%) a positive screening for neuropathic pain, 3 (9.1%) clinically relevant pain catastrophizing thoughts, 29 (87.9%) pain in ≥2 body sites and 5 (15.2%) widespread pain. Median EQoL-5D/5L index value and visual analogue scale was 0.8 (IQR 0.57-0.87) and 70 (IQR 60-80) respectively. Pain intensity was negatively correlated both to the former (Spearman Rho: -0.546, p<0.001) and to the latter (Spearman Rho: -0.387, p=0.001). A HAD anxiety and depression value over 8 were obtained in 7 (10,8 %) and 5 (7,7%) of patients, respectively.Conclusion: The incidence of new-onset pain in critically ill COVID-19 survivors is high and it was associated with a lower HRQoL. Trial registration: NCT04394169. Registered 19 May 2020. https://clinicaltrials.gov/ct2/show/NCT04394169

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