Purpose -The purpose of the research is to identify the observable operational and supply chain barriers and constraints that occur in local food supply chains, especially with smaller producers, as they seek to increase market penetration across a wider geographic area. Design/methodology/approach -The research adopts a multiple case study approach using mixed methods of data collection where case study companies are interviewed and complete a questionnaire. This process allows us to create a supply chain map and create a narrative which records the burdens and impacts occurring in local food supply chains and smaller producers looking beyond local markets. This evidence is then set against the theory of constraints (TOC) to provide a theoretical underpinning and to examine consistency of the findings. Findings -Seven broad categories of constraint type are observed: constraints due to the nature of the market; due to scale and the nature of products; constraints related to employment and skills; institutional constraints; constraints in supply chain relationships; certification, policy and regulatory constraints; and constraints around personal beliefs and anthropomorphism. Each is described as to its origin, its limitation to business and where possible, how it might be remedied. The constraints point to some counter-intuitive results as far as common perceptions of local food are concerned but suggestions for improvement are made through collaborative producer efforts, alternative institutional intervention, supply chain re-engineering and logistics innovation. Practical implications -Practical suggestions are made to improve the inclusiveness of distribution networks, to better utilise regional food groups (RFGs), to develop opportunities to set up autonomous supply chain centres, or to broaden the function of farmer co-operatives. The paper also provides an alternative model of the TOC specifically adapted for local food producers, the focus of which plays to their strengths and focuses on building competencies across, up and down the supply chain. Originality/value -The adaptation of the TOC provides an advancement of knowledge in the area of food supply chain analysis and is done in a way that is more practical in use. The paper also provides the opportunity to take a similar approach to examining other niche supply opportunities in the sector, which may be dependent on other geographically defined barriers, such as seasonal or ethnic products.

PurposeThe increasing focus on environmental sustainability and social responsibility within business agendas often leads to expectations that solutions lie in the downscaling, decentralising and deconsolidating of supply chains and logistics systems. This is no more acute than within the climate change agenda, the single biggest environmental challenge to industry today. The purpose of this paper is to challenge these notions and suggest that environmental burden actually decreases across increasing logistical scale and supply chain sophistication.Design/methodology/approachPrimary and secondary life cycle analysis and carbon auditing case evidence detailing and describing operations throughout the food supply chain is used to show what happens to resource efficiency when we chose possible “downscaling” routes.FindingsThe paper contends that the principle of economic efficiency leading to environmental efficiency (or “lean is green”) is more generally applicable against our previous expectations and that supply chain sophistication and logistical scale is more likely to lead to environmental benefit rather than cost.Practical implicationsFrom a commercial and industrial point of view, the paper provides evidence to promote conventional supply chain management good practice as a means of driving the demand needed for the technological change required to achieve climate change targets. This is good news for suppliers and distributors, particularly in the light of global economic conditions. From a consumer and policy perspective, the upshot of the paper is a call for more pragmatic thinking and a reminder that critical evidence‐based decision making should be used when judging how best to formulate supply strategies.Originality/valueThis paper represents a fresh way of thinking utilising more robust evidence amongst a set of issues that have become precariously muddled and confused.

Background and Purpose— Our aim was to identify whether particular subgroups of patients had an unacceptably high risk of symptomatic intracranial hemorrhage or low chance of benefit when treated with alteplase (recombinant tissue-type plasminogen activator). Methods— Third International Stroke Trial was an international randomized trial of the intravenous (IV) recombinant plasminogen activator alteplase (0.9 mg/kg) versus control in 3035 (1515 versus 1520) patients. We analyzed the effect of recombinant tissue-type plasminogen activator on 6-month functional outcome, early death, and symptomatic intracranial hemorrhage (both ≤7 days). We tested for any differences in treatment effect between subgroups by a test of interaction. Our 13 protocol prespecified subgroups were time to randomization, age, sex, stroke subtype, atrial fibrillation, early ischemic change (clinician and expert panel), prior antiplatelet use, stroke severity, diastolic and systolic blood pressure at randomization, center’s thrombolysis experience, and trial phase. Analyses were adjusted for key baseline prognostic factors. Results— There were no significant interactions in the subgroups analyzed that were consistent across all 3 outcomes. Treatment with recombinant tissue-type plasminogen activator increased the odds of symptomatic intracranial hemorrhage by a greater amount in patients taking prior antiplatelets than those who were not ( P =0.019 for test of interaction), but had no clear detrimental effect on functional outcome at 6 months in this group ( P =0.781 for test of interaction). Conclusions— Among the types of patient in the Third International Stroke Trial, this secondary analysis did not identify any subgroups for whom treatment should be avoided. Given the limitations of the analysis, we found no clear evidence to avoid treatment in patients with prior ischemic stroke, diabetes mellitus, or hypertension. Clinical Trial Registration— URL: http://www.controlled-trials.com . Unique identifier: ISRCTN25765518. http://www.controlled-trials.com/ISRCTN25765518 .

This paper discusses what infrastructuring in participatory design can contribute to processes of food system democratisation. It presents almost two years of engagement with a community-based organisation in a socio-economically deprived neighbourhood in England with the aim of developing a local food hub. It documents how the collaborative work shifted from setting up an infrastructure to ongoing infrastructuring of an enabling environment to grow and sustain social innovation. While the former focused on a technological platform and a business to deliver inclusivity, customer experience, and marketing, the latter focuses on building lasting relationships on three levels: strengthening ties within the community-based organisation, offering social spaces to connect with the local community, and with other organisations by forming coalitions with mutual benefits. We contribute three design opportunities: First, in order to infrastructure the formation of publics around food initiatives, we need to design for relationship building. Second, we point to design implications for ethical aspirations, participation, and system transformation towards a food democracy. Finally, we reflect on the sustainability of infrastructuring and the role of designers to work towards independent infrastructures.

This study provides an empirical assessment of the United Kingdom (UK) manufacturing small and medium-sized enterprises (MSMEs) sector, exploring the impact of environmental turbulence specific to the post–Great Recession (2008) era on changes to the way manufacturing strategy is formulated and implemented. The study identifies changes to the frequency, fluidity, formality and focus of manufacturing strategy review and how the various business functions play a changing role in contributing to this strategic process. A mixed-methods research approach is applied, incorporating a survey of 104 UK-based manufacturing SMEs supported by 17 in-depth interviews with senior managers. The research uses a parallel mixed analysis of the two data sources, thereby offering an alternative to the mono-quantitative approaches to manufacturing research that have dominated. The findings show that during, and emerging from, the post–Great Recession environment, the majority of manufacturing SMEs employ a fluid, highly frequent approach to manufacturing strategy review with increasing contributions from their marketing, sales and finance business functions driven predominantly by function-specific response to changes in the external environment, although internal drivers sill influence high-level strategy, finance and human resources. The implications of the study to theory, practice and general management suggest that the MSME sector is dominated by organizations experiencing continual impact from the external environment.