This is an open access article under the terms of the Creat ive Commo ns Attri bution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
Pharmacology education currently lacks a research‐based consensus on which core concepts all graduates should know and understand, as well as a valid and reliable means to assess core conceptual learning. The Core Concepts in Pharmacology Expert Group (CC‐PEG) from Australia and New Zealand recently identified a set of core concepts of pharmacology education as a first step toward developing a concept inventory—a valid and reliable tool to assess learner attainment of concepts. In the current study, CC‐PEG used established methodologies to define each concept and then unpack its key components. Expert working groups of three to seven educators were formed to unpack concepts within specific conceptual groupings: what the body does to the drug (pharmacokinetics); what the drug does to the body (pharmacodynamics); and system integration and modification of drug–response. First, a one‐sentence definition was developed for each core concept. Next, sub‐concepts were established for each core concept. These twenty core concepts, along with their respective definitions and sub‐concepts, can provide pharmacology educators with a resource to guide the development of new curricula and the evaluation of existing curricula. The unpacking and articulation of these core concepts will also inform the development of a pharmacology concept inventory. We anticipate that these resources will advance further collaboration across the international pharmacology education community to improve curricula, teaching, assessment, and learning.
Objectives (1) To identify any demographic characteristics, which predict medicines adherence by reporting Necessity‐Concern Differential (NCD) and Self‐Reported Health (SRH) scores among Hong Kong hospital outpatients. (ii) To investigate any association between SRH and NCD in this cultural group. Methods A total of 709 outpatients completed a questionnaire consisting demographic information, SRH and Belief about Medicines Questionnaire. Findings were analysed statistically. Key findings Descriptive statistics suggested that older participants (mean age > 64 years) tended to report low SRH, but high NCD compared to younger respondents (mean age < 53 years). Males were more likely to return high SRH and NCD scores than females (56.9 versus 42.2% and 74.8 versus 64.6%, respectively). Chi‐squared tests demonstrated that socio‐economic status was not significantly associated with SRH and NCD reporting (P > 0.05). Logistic regressions indicated gender and age groups (young‐old and old‐old) were significant predictors of SRH reporting (P < 0.001). Moreover, patients with high SRH were more likely to report high NCD than those with low SRH (P = 0.02; OR = 1.53; 95%CI 1.07–2.20). This indicates that regular administration of the SRH item followed by specific questioning could enhance early identification of potential medicine non‐believers and, subsequently, non‐adherent patients who may require urgent interventions or monitoring. Conclusions Demographic characteristics and significant association between SRH and NCD reporting support our claim that SRH opens new opportunities for prompt identification of potentially non‐adherent patients. However, further interviews to determine the cause(s) of non‐adherence are necessary to validate such findings.
Objectives The aim of this study was to investigate any association between self-rated health (SRH) and general perception about medicines using the Beliefs About Medicine Questionnaire-General (BMQ-G) in Hong Kong hospital outpatients. Moreover, the study aims to demonstrate any association between social desirability bias or response (SDR) and BMQ-G, SRH reporting in this population. Methods Seven hundred and sixty-nine outpatients, who satisfied the selection criteria, were cordially invited to participate in this study by completing a combined questionnaire of demographic information, BMQ-G, SRH and SDR Set-5 in person, while waiting to collect their medications outside a Hong Kong hospital pharmacy. Results were analysed statistically. Key Findings The number of valid questionnaires returned for statistical analysis was 698. Logistic regressions indicated age groups, gender and SRH were significant predictors for BMQ-G reporting. Patients aged over 62, male or those with high SRH were less likely to present high BMQ-G scores, compared to patients aged under 45, female or those with low SRH, respectively (OR 0.43, 0.73 and 0.66, respectively, all CIs 95%). Logistic regressions also demonstrated overall BMQ-G, and SRH reporting was unlikely to be associated with SDR (all P > 0.05) although age was a significant predictor for SDR reporting (OR = 1.10; CI 95%). Conclusions This study illustrated age groups, gender and self-rated health significantly associated with general medicine beliefs reporting. The possible association between socially desirable bias and general medicine beliefs or self-rated health reporting was insignificant. attitudes or intentions towards adhering to their medical treatments. [3] Medicine beliefs could be broadly divided into general and specific. [3] General beliefs reflect patients' overall attitudes to medicines, which appear to be reasonably stable over time and independent of the changes in subjective health status. [4] Specific beliefs indicate patients' perceptions about their current medications. Interestingly, our recent study in a Hong Kong regional teaching hospital demonstrated middle-aged and older pharmacy
The complete genome sequences of Rouxiella badensis DSM 100043 T and Rouxiella chamberiensis DSM 28324 T were determined using Oxford Nanopore long-read sequencing and the Flye assembler. The former contains a circular chromosome of 4,964,479 bp and a circular plasmid of 116,582 bp; the latter contains a circular chromosome of 4,639,296 bp.
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