The use of miniscrews for orthodontic anchorage combined to periodontal treatment in aggressive periodontitis: case report and review of the literature. Introduction: Miniscrews (MSs) have gained rapid popularity among orthodontic specialists over the past decade. Subsequently, as general dental practitioners continue to provide general care for patients undergoing orthodontic treatment they are likely to encounter MSs. Observation: A 60-year-old woman concerned about generalized agressive periodontitis (generalized periodontitis stage-III) with complaints of diastema and spacing in the upper arch, received for ten years nonsurgical therapy via scaling and root planning combined with systemic antibiotics. Maxillary periodontal flaps achieved this primary periodontal treatment. As she complained of protrusion of her maxillary incisors she was referred for orthodontic treatment with palatinal MSs to retract and align the maxillary anterior segment. A 26 months follow-up showed esthetic and functional stability of the result. Discussion: This case report demonstrates efficacity of combined periodontal and orthodontic treatments using palatinal MSs in order to successfully contribute to treatment of stage-III periodontitis.