Xanthine calculi are uncommonly encountered stones. When they occur, they typically do so in association with inborn metabolic disorders such as hereditary xanthinuria or Lesch-Nyhan syndrome. They may also occur in association with states of profound hyperuricemia such as myeloproliferative disease after treatment with allopurinol. If the underlying disorder is not addressed, a high risk of stone recurrence exists. Therefore, to raise clinical awareness, we reviewed and report our experience in the treatment of patients with these stones, discussing the underlying pathophysiology and approach to treatment.
We argue that there is scholarly potential in linking theory on industry clusters with theory on value networks. To date, these two theoretical streams have developed largely in parallel, limiting understanding of how the two are integrated in practice. By considering these theories in combination and the unique context of creative industries, we generate insight on the management of clusters as value networks. Our ongoing longitudinal empirical case is a new media cluster called ‘Mediapolis’ in the city of Tampere, Finland. The case study commenced at the time the cluster was in the planning and early operational stage. Results demonstrate the usefulness of linking the two theories, and support a future research agenda examining the types of cluster configurations meeting the criteria of value networks, and the conditions under which value network cluster configurations are more sustainable than simply a spatial agglomeration of clusters.
Media management scholarship has achieved increasing maturity in recent years. While acknowledging significant accomplishment, the essay provides a critical assessment to stimulate discourse in the field about what is needed to achieve next stage development in theorisation and relevance for practice. The authors present four parables to illustrate the importance of what they suggest: (1) benefitting societies as well as media industries, and thus more carefully considering our intended role as researchers and educators, (2) building theory that is multidisciplinary and of broader relevance in the social sciences, (3) broadening the methods we employ in research, and (4) challenging ourselves and our students to be more ambitious in our commitments and intentions.
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