corporate social performance, family firms, stakeholder theory,

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The planning and implementation of an enantioselective total synthesis of (+)-scholarisine A is presented. Key tactics employed include a novel cyclization, consisting of a nitrile reduction coupled with concomitant addition of the resultant amine to an epoxide; a modified Fischer indolization; an oxidative-lactonization of a diol in the presence of an indole ring; and a late stage cyclization to complete the caged ring scaffold. The development of a possible “retrobiosynthetic” approach to other members of the akuammiline alkaloid family is also described.