The study is devoted to the development of approach to comprehensive assessment of the regional agro-food industry development problems. This task was solved using the methods of expert assessment and statistical analysis of their results. We have substantiated a system of agro-food industry development indicators, which covers the level of enterprises and the level of government. Approbation of the proposed approach using the example of the Republic of Crimea revealed the key problems. At the enterprise level: low level of development of advanced technologies, low share of innovative products, ineffective organization of cause-and-effect analysis, insufficient scientific feasibility of technological processes. At the state level: insufficiently effective state regulation in the field of import substitution, insufficient stimulation of demand for domestic products of the processing industry of the agro-industrial complex (AIC), insufficient state stimulation of the production of highquality domestic products, insufficient level of scientific research support. This allows determining the priority directions for the development of recommendations and the implementation of actions to ensure the regional agro-food industry development.

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