Genital herpes is the most common cause of ulcers in sexually transmitted diseases (STDs). It is presented as a single or multiple, painful injury, accompanied by bilateral, also painful, lymphadenopathy. In immunocompromised patients, such as those affected by HIV, Herpes Simplex Virus (HSV) infections have a variety of clinical manifestations; they may be located, scattered or atypical. In addition, lesions may be more extensive and persistent than HIV-negative patients. We present two cases of immunocompromised patients with perianal herpetic ulcers, one HIV carrier, and the other with leukopenia caused by visceral Leishmaniasis.

SUMMARYDermatitis herpetiformis or Duhring-Brocq disease is a chronic, autoimmune, pleomorphic disease, characterized by lesions on extension surfaces, accompanied by intense pruritus, and is usually associated with celiac disease, gluten sensitivity, gluten sensitivity ataxia and some forms of IgA neuropathy. Two cases of dermatitis herpetiformis are presented in female patients and we make a brief review of the literature on the treatment of this pathology.