The Qarhan potash‐magnesium salt deposit, which consists from east to west of four playa districts, namely Huobuxun, Qarhan, Dabuxun and Bieletan, may be divided from bottom to top into three salt beds (S1 S2 and S3), with potash salts mainly occurring in S3 The paper lays emphasis on the evolutionary history of the deposition of Salt Bed S3 and the modes of formation of potash salts in the Qarhan playa.The analysis of the data obtained from more than 170 boreholes and the geochemical studies on bromine, magnesium and calcium reveal the existence of four concentration stages and three dilution stages during the formation of the Upper Salt Bed S3. In the process of concentration, evaporation of brine and precipitation of salt minerals dominated, which obeyed the regularity indicated by the phase diagram of the quaternary system Mg‐Na‐K/Cl−H2O. In the dilution stages, however, mixing of brines, dissolution of salts (especially the playa) and mechanical clastic deposition played the leading role. The prerequisite for mixing in the Qarhan salt deposit lies in that chloride type brine of the northeastern part coexists with magnesium sulfate type brine of the southwestern part in the same salt lake. The appearance of bassanite has verified the process of mixing. The dissolution refers to the partial dissolution of the salt beds originally deposited. Particularly in the last dilution process, approximately 200 km2 of the playa north of the Tuanjie Lake had been dissolved before a new‐born lake took form.Solid potash salts were formed in three ways: (1) The surficial brine of the Dabuxun lake coexistent with the playa had an intercompensational relationship with the intercrystalline brine in the playa. As a result, K+ ions were collected into the lake, and layered carnallite precipitated from lake brine during the seasons of evaporation, which was accelerated by the action of wind. (2) Disseminated potash‐magnesium salts were formed by further concentration of intercrystalline brine. (3) Dissolution and reformation of the playa resulted in the formation of a new‐born salt lake, in the drying of which brine collected the potash‐magnesium salts originally dispersed over the playa into local low‐lying areas, forming finally stratoid potash‐magnesium salts.
Background: While chemotherapy-induced alopecia is considered temporary and usually reversible within 1-6 months after chemotherapy, some patients report persistent alopecia several years after chemotherapy. The frequency of long-term permanent chemotherapy-induced alopecia (PCIA) and hair related changes is unknown. This study aimed to assess the incidence of PCIA among breast cancer patients by quantifying changes in hair density and thickness before chemotherapy, after two cycles of chemotherapy, and one, three, six, and 36 months after completion of chemotherapy. Methods: This was a prospective cohort study of 61 patients 18 years of age or older with a postoperative diagnosis of stage I to III breast cancer who received adjuvant chemotherapy between February and September 2012 at an outpatient breast cancer clinic in Korea. Objective hair density and thickness were measured using a noninvasive bioengineering device. Results: At 6 months after completion of chemotherapy, 11.5% and 30.8% of patients experienced PCIA in terms of hair density and thickness, which did not recover until after 36 months after completion of chemotherapy. Patients who received a combination of doxorubicin and cyclophosphamide followed by four additional cycles of paclitaxel were more likely to experience PCIA compared to patients with other type of chemotherapy. Patients who had PCIA were more likely to have significantly lower body image compared to patients without PCIA. Conclusions: Permanent and severe alopecia is a common side effect of breast cancer adjuvant chemotherapy. Additional research is necessary to translate these findings into interventions for improving distress due to permanent alopecia in breast cancer patients after completion of chemotherapy.
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