Breast mass is one of the most distinctive signs for the diagnosis of breast cancer, and the accurate segmentation of masses is critical for improving the accuracy of breast cancer detection and reducing the mortality rate. It is time-consuming for a physician to review the film. Besides, traditional medical segmentation techniques often require prior knowledge or manual extraction of features, which often lead to a subjective diagnosis. Therefore, developing an automatic image segmentation method is important for clinical application. In this paper, a fully automatic method based on deep learning for breast mass segmentation is proposed, which combines densely connected U-Net with attention gates (AGs). It contains an encoder and a decoder. The encoder is a densely connected convolutional network and the decoder is the decoder of U-Net integrated with AGs. The proposed method is tested on the public and authoritative database-Digital Database for Screening Mammography (DDSM) database. F1-score, mean intersection over union, sensitivity, specificity, and overall accuracy are used to evaluate the effectiveness of the proposed method. The experimental results show that dense U-Net integrated AGs achieve better segmentation results than U-Net, attention U-Net, DenseNet, and state-of-the-art methods. INDEX TERMS Breast masses segmentation, deep learning, biomedical image processing, attention gates, densely connected convolutional network.
Breast cancer is the leading cause of cancer death in women, and early detection can reduce mortality. Architectural distortion (AD) is a feature of clinical manifestations for breast cancer, however, due to its complex structure and low detection accuracy, which cause a high mortality of breast cancer. In order to improve the accuracy of AD detection and reduce the mortality of breast cancer, this paper proposes a new method by combining the non-subsampled contourlet transform (NSCT) with the improved pulse coupled neural network (PCNN). Firstly, the top–bottom hat transformation and the exponential transformation are employed to enhance the image. Secondly, the NSCT is employed to expand the overall contrast of the mammograms and filter out the noise. Finally, the improved PCNN by the maximum inter-class variance threshold selection method is employed to complete the AD detection. This proposed approach is tested on the public and authoritative database—Digital Database for Screening Mammography (DDSM). The specificity of the method is 98.73%, the accuracy is 93.16%, and the F1-score is 79.80%, and the area under curve (AUC) of the receiver operating characteristic (ROC) curve is 0.93, these results clearly demonstrate that the proposed method is comparable with those methods in recent literatures. This proposed method is simple, furthermore it can achieve high accuracy and help doctors to perform computer-aided detection of AD effectively.
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