A 47-year-old male presented with haematuria and flank pain for two weeks. Ultrasonography and renal scan revealed a poorly functioning left kidney with multiple calculi. Simple nephrectomy was performed and the specimen revealed a mass in his renal pelvis which showed both carcinomatous and sarcomatous components on microscopy. The sarcomatous component consisted of diffuse pleomorphic osteoblasts with intervening lacy osteoid, giving an osteosarcoma-like appearance. These areas of tumour were strongly positive for vimentin and osteopontin. The carcinomatous component was transitional cell carcinoma. Patchy areas of squamous cell carcinoma which were positive for pancytokeratin on immunostaining were also seen. Few weeks later, the patient presented with metastatic lesions in the sacrum. After nephrectomy, the patient underwent palliative radiotherapy of the spine followed by sunitinib therapy. A month later, there was recurrence at the site of surgery. The patient succumbed to his illness within five months of diagnosis. This report describes an extremely rare case of carcinoma, renal pelvis with predominantly osteosarcomatous areas.

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The Ewing family of tumors includes classic Ewing Sarcoma (ES), atypical ES, primitive neuroectodermal tumor (PNET), and Askin tumor. It is a small round blue cell tumor involving most commonly the diaphyses of long bones. We present a series of four cases of ES occurring at rare sites.

BACKGROUND Giant Cell carcinoma is a variant of Sarcomatoid carcinoma which occurs at a younger age and predominantly in smoker males. Metastasis and wide spread extension is common by the time of diagnosis and is associated with a poor outcome. Fine needle aspiration cytology (FNAC) has a great role in diagnosing Giant cell carcinoma which are not amenable for surgical excision and early diagnosis by FNAC will greatly influence of the survival rate as treatment can be started immediately. We report a case of Giant Cell Carcinoma diagnosed by FNAC in a 55 yrs. male who presented with lung mass in the periphery of right lower lobe associated with overlying rib destruction.