A range of medium-sized cyclic ethers (5 to 11 membered) have been effectively synthesized through intramolecular reductive coupling of dialdehydes initiated by 50 ppm to 0.5% of AgNTf2 with hydrosilane at 25 °C. The catalytic system is also suitable for the coupling of two different monoaldehydes to provide unsymmetrical ethers. This protocol features broad functional group compatibility, high product diversity, high efficiency, and utility in the late-stage modification of complex biorelevant molecules.

An efficient method for the synthesis of 1,4-ketoaldehydes via cross-coupling of N-alkenoxyheteroarenium salts and primary aldehydes is developed. This method works with broad substrate scope and excellent functional group compatibility....

A range of unsymmetrical and symmetrical disiloxanes have been effectively synthesized through oxidative coupling of hydrosilanes with DMF as a source of oxygen catalyzed by 0.5% AgNTf2 at 60 oC....