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Food allergy is defined as an immune-mediated response to food. Food allergy after solid organ transplantation was first described in 1997 after liver and kidney transplantation. A three years- five-month-old male was admitted with swelling of the lip after food intake. He had received a liver transplant from a living donor at ten months of age due to biliary atresia. Treatment with tacrolimus and mycophenolate mofetil was monitored, and he was admitted to the emergency department with complaints of swelling of the lip that developed immediately after eating eggs in our department at 20 months of age. No associated respiratory, skin, or gastrointestinal findings were observed in the case, who had previously consumed eggs without problems. Later, after consuming honey and tahini mixture, corn with mayonnaise sauce at different times, swelling developed on his lips and eyes. According to tests, egg, peanut, and hazelnut were excluded from the patient's diet. The case was followed up with diet therapy for two years without any problems. Organ donors should be screened for food allergies to predict the risk of organ recipients for new food allergies after transplantation. Although there is no evidence of food allergies in the donor, it should be kept in mind that new food allergy may develop in patients who have undergone solid organ transplantation, and patients should be followed up in this regard.

Objectives Large cell calcifying Sertoli cell tumours (LCCSCTs) are one of the infrequent causes of prepubertal gynaecomastia. Most of these tumours are in the content of Peutz–Jeghers syndrome (PJS) or other familial syndromes (Carney complex). Case presentation Here, we report a long-term follow-up of an 8.5-year-old prepubertal boy with a diagnosis of PJS, who presented with bilateral gynaecomastia, advanced bone age and accelerated growth velocity, and were found to have bilateral multifocal testicular microcalcifications. As the findings were compatible with LCCSCT, anastrozole was initiated. Gynaecomastia completely regressed and growth velocity and pubertal development were appropriate for age during follow-up. Testicular lesions slightly increased in size. After four years of medication, anastrozole was discontinued but was restarted due to the recurrence of gynaecomastia after six months. Conclusions Testicular tumour should be investigated in a patient with PJS who presents with prepubertal gynaecomastia. When findings are consistent with LCCSCT, aromatase inhibitors may be preferred in the treatment.

Objective: Obesity critically affects the quality and expectancy of life with its physiological, hormonal, metabolic, and social aspects. This study has assessed the success rate of exogenous obesity management consisting of lifestyle changes with an intensive follow-up in prepubertal children. Methods: Twenty-two obese prepubertal children between ages 4 and 9 years were enrolled in this study. Eating habits were surveyed, and individually tailored diet programs were introduced. Additionally, an exercise coach prepared individualized exercise programs. Patients were recalled monthly for six months. At each monthly visit, weight, height, BMI, waist circumference, body fat percentages were measured, and compliance with the diet and exercise programs was reviewed. Wilcoxon signed-rank test was used for statistical analysis. Results: The patients showed statistically significant reductions in BMI, waist circumference, and body fat percentage (p<0.001 for each). Conclusion:This study demonstrates that in prepubertal obese children, lifestyle changes implemented by intensive follow-up and monitoring could increase the success rate of exogenous obesity management.

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