This study was undertaken to study the correlation between imprint cytology, crush smears and histopathology in endobronchial growths using fiberoptic bronchoscopy. Methods: The study was conducted in the Department of Internal Medicine and Pathology at Sher-i-Kashmir Institute of Medical Sciences. Eighty-one patients with clinical and radiological evidences of lung lesions were enrolled. From all patients five pieces of tissue were obtained during fiberoptic broncoscopy which revealed an endobronchial growth. From each bit of tissue an imprint and crush smear were prepared by imprinting the tissue on a clean surface of glass slide without compressing the tissue while as crush smear was made by gently crushing the tissue between two glass slides. The tissue specimens were then placed in formaldehyde solution for histological examination. Standard statistical methods were used to analyze the data (chi-square (χ 2) analysis; a Fisher's exact test was used to evaluate the data if more than 25% of the expected values were <5). The level of significance selected was P<0.05. Results: Overall 49 cases (60.49%) were diagnosed as malignant and 31 cases (38.2%) as benign on histopathology. In one case with active bleed, smears were taken from blood clots and bronchoalveolar lavage was done, both of which revealed malignancy. Forty histopathologically proven malignant cases were positive for malignancy (81.6%) on crush smear cytology, while nine cases were not. Imprint smears were positive for malignant cells in 41 cases out of 49 histologically proven malignant cases (83.6%) and eight cases did not show malignant cells on imprint. The sensitivity, specificity, positive predictive value and negative predictive value of crush smear results were 81.6%, 100%, 100% and 77.5% respectively. Conclusion: Imprint and crush cytology are rapid, reliable and accurate techniques. The technique can improve the diagnostic accuracy in endobronchial lesions, as it is faster and more cost effective.