The purpose of this study was to compare the effects of sprint interval training (SIT) and continuous endurance training (CET) on selected anthropometric, aerobic, and anaerobic performance indices as well as the blood lipid profile, inflammatory and muscle damage markers in healthy young males. Fifteen recreationally active male volunteers (age: 21.7 ±2.2 years, body mass: 83.0 ±8.0 kg, body height: 1.82 ±0.05 m) were divided into two groups according to their initial VO2max levels. Training programs were conducted 3 times per week for 7 weeks. The SIT program consisted of 4–6 Wingate anaerobic sprints with a 4.5 min recovery, while CET consisted of 30–50 min cycling at 60% VO2max. Biochemical, anthropometric and fitness assessments were performed both pre and post-intervention. Significant improvements in VO2max, anaerobic power and capacity, and VO2 utilization during the submaximal workout and significant decreases in body fat and in waist circumference after the intervention occurred in both SIT and CET groups. Significantly greater gross efficiency was measured in the CET group. No differences in the lipid profile or serum levels of inflammatory, myocardial and skeletal muscle damage markers were observed after the training period. The study results agree with the effectiveness of a 30 s all-out training program with a reduced time commitment for anthropometric, aerobic and anaerobic adaptation and eliminate doubts about its safety as a model.

Purpose: Recent studies have demonstrated that modifying the 'classic' 6x30-s 'all-out' sprint interval training (SIT) protocol by incorporating either shorter sprints (6x10-s or 15-s sprints) or fewer sprints (e.g. 2x20-s sprints; reduced-exertion high-intensity interval training (REHIT)) does not attenuate the training-induced improvements in maximal aerobic capacity (VȮ2max). The aim of the present study was to determine whether reducing the sprint duration in the REHIT protocol from 20 s to 10 s per sprint influences acute affective responses and the change in VȮ2max following training. ) were randomised to a group performing a 'standard' REHIT protocol involving 2x20-s sprints or a group who performed 2x10-s sprints. VȮ2max was determined before and after 6 weeks of 3 weekly training sessions. Acute affective responses and perceived exertion were assessed during training. Methods Results: Greater increases in

BackgroundParaoxonase 1 (PON1) is an antioxidant enzyme that protects high-density lipoprotein (HDL) and low-density lipoprotein against oxidation. Limited studies have addressed the influence of exercise on PON1 activity and its relationship with PON1 phenotypes. We investigated relationships between PON1-192 phenotypes, PON1 activity, aerobic exercise, and blood lipid and lipoprotein concentrations in middle-aged women.MethodsAn exercise group (n = 50) engaging in regular aerobic exercise and a control group (n = 41) were selected from a subset of 300 Caucasian women that met the inclusion criteria. Serum PON1, salt-stimulated PON1 (SSPON1), and arylesterase (ARE) activities; cholesterol levels and ARE activities of total HDL and HDL subgroups (HDLs) (supernatants obtained by polyethylene glycol); and blood lipid and lipoprotein concentrations were determined by standardized enzymatic methods. PON1-192 QQ (low activity), QR (moderate activity), and RR (high activity) phenotype groups were defined using serum SSPON1/ARE activity ratios. The R-carries (RC) phenotype group consisted of the QR and RR groups combined.ResultsAll lipid and lipoprotein concentrations were greater in the exercise group than in the control group. Regardless of phenotype, no significant differences were observed between the exercise and control groups in terms of serum PON1, SSPON1, or ARE activity associated with HDLs (p > 0.05), whereas PON1 activities in QQ-phenotyped women in the exercise group were significantly higher than those in the control group (p < 0.01), but not the RC group. A statistically significant interaction between PON1 phenotypes (QQ and RC groups) and exercise (exercise and control groups) on PON1 activity was found.ConclusionThese results showed that a regular aerobic exercise program can improve PON1 activity depending on PON1-192 phenotype, but not on lipid and lipoprotein levels, in middle-aged Turkish women.

The ergogenic effects of carbohydrate (CHO) and caffeine (CAF) mouth rinse (MR) methods on anaerobic performance remains unclear. Therefore, the aim of this study was to investigate the effects of CHO, CAF, and CHO + CAF combination solutions in mouth on repeated vertical jumping (RVJ) performance in highly trained male athletes. Eight male athletes (mean age: 22 years) underwent test sessions four times with minimum 24-h intervals under fasting conditions. Participants rinsed their mouths with four different 25-ml solutions, namely, CHO (6.4% maltodextrin = 1.6 g), CAF (1.2% caffeine = 300 mg), placebo (PLA, saccharin), or CHO + CAF (6.4%+1.2%) combination, for 10 s and performed a 30-s RVJ test twice with a 5-min interval. Peak power output, vertical jump height, blood lactate level, fatigue index, and rate of perceived exertion of the RVJ tests for different intervention sessions were compared. The statistical significance level was set at p ≤ 0.05. Analyses demonstrated that CHO-(Δ: 3.4), CAF-(Δ: −0.8), and CHO + CAF-MR (Δ: −1.8) interventions led to similar RVJ performance changes compared to PLA. All differences in the dependent variables were statistically insignificant and had moderate and lower effect sizes between interventions (p > 0.05, g < 0.94). Our study did not elicit sufficient evidence to recommend highly trained male athletes the use of CHO-and CAF-MR separately or in combination to enhance jump performance. However, the fact that some differences have medium to large effect sizes suggests that the issue is still worth to be a potential topic for further research. Highlights. Effects of CHO + CAF-MR on anaerobic performance in highly trained athletes have not been investigated using performance tasks requiring high technical skills. . There is not enough evidence to suggest that CHO, CAF and CHO + CAF-MR interventions have beneficial effects on RVJ performance compared to PLA in highly trained male athletes. . Some statistically insignificant differences have medium to large effect sizes. Therefore, the issue is still worth to be a potential topic for further research.

Results: In the analyses wherein baseline weight was carried forward for missing data, the IBT produced significantly larger mean weight loss in comparison to the EE at the end of the 8 weeks [2.28 kg (2.11) vs. 0.74 kg (1.57), p=0.001]. The participants in the IBT group, when compared to the EE group, were also more likely to achieve a clinically significant weight loss of 5% of their initial body weight at the end of the 8-week study period (17.6% vs. 2%, p=0.016). Conclusion: The participants who received a structured IBT intervention lost significantly more weight after two months, compared to those who received weekly informational emails regarding weight loss. Internet-based behavioral therapy programs may have the potential to serve as a low-cost alternative for obese patients.