Objective: To assess prevalence and factors associated with depression, anxiety and stress among adolescents experiencing lockdown during the 2019 coronavirus disease 2019 (COVID-19) in both Asian and Western countries. Material and Methods: From May-June 2020, secondary school students were enrolled in an online cross-sectional survey, through social media; including, but not limited to, Instagram, Snapchat, WhatsApp and LINE. We assessed the presence and severity of depression (Patient Health Questionnaire-9), anxiety (Generalized Anxiety Disorder Scale-7) and stress (Perceived Stress Scale-10) within the last month, and assessed significant associations with demographics, degree of social distancing, and other associated issues using univariate and multivariate logistic regression analyses.Results: From 392 respondents (56.4% male, 43.1% female), from Thailand (59.2%), the United Kingdom (26.5%) and other countries (14.3%), we identified depressive symptoms in 58.7%, anxiety in 40.3% and high levels of stress in 9.7%. By multivariate analysis, we found significant associations between being female and depression and anxiety, being in late secondary school years and depression, and changes in patterns of substance use and anxiety and stress. Participants not located in Thailand had increased risk of depression.Conclusion: Our study demonstrated depression, anxiety and stress in six, four and one out of ten adolescents, respectively, who were experiencing lockdowns due to the COVID-19 pandemic. We found female gender, older school years, and changes in substance use patterns to be significantly associated with these mental health conditions.

Background: Stressors introduced to adolescents by COVID-19 social distancing measures may cause mental health problems to (re)surface. We studied depression, anxiety and stress among adolescents experiencing lockdown. Methods: From May-June 2020, secondary school students were enrolled in an online cross-sectional survey through social media. We assessed presence and severity of depression (PHQ-9), anxiety (GAD-7) and stress (PSS-10) in the last month, demographics, degree of social distancing, and other associated issues.Results: Of 392 respondents (56.4% male, 43.1% female), mostly from Thailand (59.2%) and UK (26.5%). We identified depressive symptoms in 58.7%, anxiety in 40.3% and high levels of stress in 9.7%. We found, by multivariate analysis, significant associations between being female and depression and anxiety, being in late secondary school years and depression, and changes in patterns of substance use and anxiety and stress.Conclusions: We propose that girl-centred mental health support platforms should be readily available and tailored to fit specific countries’ contexts. Schools must closely monitor and act upon any concerns which arise from their students and must also monitor mental health wellbeing as changes in academic routine due to COVID-19 could be drastic for some. Harm reduction services must adapt and utilise innovative telemedicine interventions, tailored towards adolescent users.