The objective of the present study was to investigate the clinical application of magnetic resonance imaging (MRI)-respiratory gating technology for assessing illness severity in children with obstructive sleep apnea hypopnea syndrome (OSAHS).MRI-respiratory gating technology was used to scan the nasopharyngeal cavities of 51 children diagnosed with OSAHS during 6 respiratory phases. Correlations between the ratio of the area of the adenoid to the area of the nasopalatine pharyngeal cavity (Sa/Snp), with the main indexes of polysomnography (PSG), were analyzed. Receiver operator characteristic (ROC) curve and Kappa analysis were used to determine the diagnostic accuracy of Sa/Snp in pediatric OSAHS.The Sa/Snp was positively correlated with the apnea hypopnea index (AHI) (P < .001) and negatively correlated with the lowest oxygen saturation of blood during sleep (LaSO2) (P < .001). ROC analysis in the 6 respiratory phases showed that the area under the curve (AUC) of the Sa/Snp in the end-expiratory phase was the largest (0.992, P < .001), providing a threshold of 69.5% for the diagnosis of severe versus slight-moderate OSAHS in children. Consistency analysis with the AHI showed a diagnosis accordance rate of 96.0% in severe pediatric OSAHS and 96.2% in slight-moderate pediatric OSAHS (Kappa = 0.922, P < .001).Stenosis of the nasopalatine pharyngeal cavity in children with adenoidal hypertrophy was greatest at the end-expiration phase during sleep. The end-expiratory Sa/Snp obtained by a combination of MRI and respiratory gating technology has potential as an important imaging index for diagnosing and evaluating severity in pediatric OSAHS.
To evaluate the correlation between mean platelet volume (MPV) and obstructive sleep apnea-hypopnea syndrome (OSAHS) in children, and to explore the diagnostic value of MPV for OSAHS. Children with OSAHS diagnosed by polysomnography (PSG) at Fuyong People's Hospital of Bao'an District/Shenzhen Children's Hospital from January 2020 to January 2021 were enrolled in this study. MPV in peripheral venous blood of the enrolled children was detected. Based on the PSG results (apnea-hypopnea index [AHI] and lowest oxygen saturation [LSaO 2 ]), illness severity was classified, and correlations between the 2 parameters were statistically analyzed. A total of 190 children (males = 135, females = 55) with OSAHS were enrolled in the study. There were no significant correlations between AHI, LSaO 2, white blood cell count, red blood cell count, blood platelets, hemoglobin, and packed cell volume (P > .05), but there was a significant positive correlation between AHI and MPV (R > 0, P < .05). There was a significant negative correlation between the LSaO 2 index and MPV (R > 0, P < .05). In addition, the receiver operating characteristic (ROC) curve indicated that the best cutoff value for MPV to diagnose mild and moderate-to-severe disease conditions was 9.35 fl, and the coincidence rates for these 2 disease conditions were 93% and 80%, respectively. The ROC curve was also optimal for the diagnosis of mild and moderate-to-severe hypoxia. The critical value was 8.85 fl, and the coincidence rates for these 2 conditions were 96.4% and 76.3%, respectively. In children with OSAHS, MPV is positively correlated with AHI and negatively correlated with the LSaO 2 index of PSG. Based on the results of ROC curve analysis, MPV can be used as an auxiliary diagnostic index to judge the severity of OSAHS and the degree of hypoxia in children.Abbreviations: AHI = apnea-hypopnea index, LSaO 2 = lowest oxygen saturation, MPV = mean platelet volume, OSAHS = obstructive sleep apnea-hypopnea syndrome, PSG = polysomnography, RBC = red blood cell count, ROC = receiver operating characteristic.
Abstract-IGBT (insulated-gate bipolar transistors) deadtime compensation circuit has a very important significant for improving the output voltage waveform of the inverter, reducing the harmonic output current. Thus, many compensation strategies are reported in literatures and have been implemented in industrial drives recently. Overall, the method of dead-time compensation can be divided into hardware compensation and software compensation. Hardware compensation method needs additional hardware circuits, which means additional space and cost. Still more, the additional circuit is easy to interfere with others, which can reduce the compensation accuracy. While the software compensation method takes up a lot of memory space and additional input-output ports of processor, which often result to the added operation and heat dissipation of controller. In this paper, CPLD (complex programmable logic device)-based circuit design of dead-time compensation is presented to solve these existed drawbacks. It is verified that not only can the circuit simplify existed inverter dead-time compensation design, but also it has the advantages of small volume, strong antiinterference ability, and high compensation precision. The simulation results validate that this method is feasible and effective.
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