No abstract

Carbon monoxide can produce different patterns of brain injury in the acute and delayed stages. CT and MRI are valuable in the delineation of disease extent and helpful for understanding the pathophysiologic mechanisms.

Delayed treatment and postoperative varus alignment were major factors contributing to AVNFH in our series. Early treatment and anatomical fixation of displaced SFFN are essential for diminishing the risk of AVNFH development.

Our results indicate that treatment with oral glucosamine sulfate in a rat OA model (1) attenuates the development of OA, (2) concomitantly reduces nociception, and (3) modulates chondrocyte metabolism, possibly through inhibition of cell p38 and JNK and increase of ERK expression.