Sharing of research data in public repositories has become best practice in academia. With the accumulation of massive data, network bandwidth and storage requirements are rapidly increasing. The ProteomeXchange (PX) consortium implements a mode of centralized metadata and distributed raw data management, which promotes effective data sharing. To facilitate open access of proteome data worldwide, we have developed the integrated proteome resource iProX (http://www.iprox.org) as a public platform for collecting and sharing raw data, analysis results and metadata obtained from proteomics experiments. The iProX repository employs a web-based proteome data submission process and open sharing of mass spectrometry-based proteomics datasets. Also, it deploys extensive controlled vocabularies and ontologies to annotate proteomics datasets. Users can use a GUI to provide and access data through a fast Aspera-based transfer tool. iProX is a full member of the PX consortium; all released datasets are freely accessible to the public. iProX is based on a high availability architecture and has been deployed as part of the proteomics infrastructure of China, ensuring long-term and stable resource support. iProX will facilitate worldwide data analysis and sharing of proteomics experiments.

The Tibetan Plateau (TP), the highest and largest plateau in the world, with complex and competing cryospheric‐hydrologic‐geodynamic processes, is particularly sensitive to anthropogenic warming. The quantitative water mass budget in the TP is poorly known. Here we examine annual changes in lake area, level, and volume during 1970s–2015. We find that a complex pattern of lake volume changes during 1970s–2015: a slight decrease of −2.78 Gt yr−1 during 1970s–1995, followed by a rapid increase of 12.53 Gt yr−1 during 1996–2010, and then a recent deceleration (1.46 Gt yr−1) during 2011–2015. We then estimated the recent water mass budget for the Inner TP, 2003–2009, including changes in terrestrial water storage, lake volume, glacier mass, snow water equivalent (SWE), soil moisture, and permafrost. The dominant components of water mass budget, namely, changes in lake volume (7.72 ± 0.63 Gt yr−1) and groundwater storage (5.01 ± 1.59 Gt yr−1), increased at similar rates. We find that increased net precipitation contributes the majority of water supply (74%) for the lake volume increase, followed by glacier mass loss (13%), and ground ice melt due to permafrost degradation (12%). Other term such as SWE (1%) makes a relatively small contribution. These results suggest that the hydrologic cycle in the TP has intensified remarkably during recent decades.