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Antibacterial photocatalytic therapy (APCT) is considered to be a potential treatment for administrating antibiotic‐resistant bacteria. However, due to the low photocatalytic efficiency and weak ability to capture bacteria, it is not practically applied. In this work, an organic–metal oxide hybrid semiconductor heterostructure is fabricated for the photocatalytic generation of reactive oxygen species (ROS) to kill the drug‐resistant bacteria. The organic semiconductor, perylene diimide (PDI), can self‐assemble on Sn3O4 nanosheets to form a “hook‐and‐loop” sticky surface that can capture bacteria, via large numbers of hydrogen bonding and π–π stacking interactions, which are not possible in inorganic semiconductors. This easy‐to‐fabricate hybrid semiconductor also possesses improved photocatalytic activity, which is owing to the formation of heterostructure that achieves full‐spectrum absorption, and the reduction of the photocarrier recombination rate to produce more reactive oxygen species. It has a good promoting effect on the wounds of mice infected by Staphylococcus aureus. This work shows new ideas for fabricating smart full‐spectrum inorganic–organic hybrid adhesive heterostructure photocatalysts for antibacterial photocatalytic therapy.

A simple protocol to distinguish enantiomers is extremely intriguing and useful. Herein, we report on a method for the visual recognition of 3,4-dihydroxyphenylalanine (Dopa) enantiomers. It is based on the chirality of L-cysteine-capped gold nanoparticles (L-Cys-capped AuNPs) that can be used as a chiral selector for L-and D-forms of Dopa. On addition of L-Dopa to a solution of the L-Cys-capped AuNPs, a color change from red to blue can be seen, while no color change is found on addition of D-Dopa. The chiral recognition can be achieved by eye and simple spectrophotometry. Notably, this method does not require complicated chiral modification. The method excels through its low-cost, good availability of materials, and its simplicity.

The ability to recognize and quantify the chirality of alpha-amino acids constitutes the basis of many critical areas for specific targeting in drug development and metabolite probing. It is still challenging to conveniently distinguish the enantiomer of amino acids largely due to the lack of a universal and simple strategy. In this work, we report a strategy for the visual recognition of α-amino acids. It is based on the chirality of L-tartaric acid-capped gold nanoparticles (L-TA-capped AuNPs, ca. 13 nm in diameter). All of 19 right-handed α-amino acids can induce a red-to-blue color change of L-TA-capped AuNP solution, whereas all of the left-handed amino acids (except cysteine) cannot. The chiral recognition can be achieved by the naked eye and a simple spectrophotometer. This method does not require complicated chiral modification, and excels through its low-cost, good availability of materials and its simplicity. Another notable feature of this method is its high generality, and this method can discriminate almost all native α-amino acid enantiomers. This versatile method could be potentially used for high-throughput chiral recognition of amino acids.