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Objective: Diabetic feet and toe deformities is commonly associated with diabetes mellitus and neuropathy is the causative factor combined with vasculopathy. In this study we list out various morphological changes which occur in Diabetic foot lesions, the pathophysiology and the management of the deformed toes and feet. Materials and Methods:A prospective study was carried out in patients presenting to the Diabetic Clinic at a tertiary care hospital in Delhi. 70 patients who were labelled as diabetics formed the study group. Results:The most common age group affected belonged to 51-60 age bracket which included 41 patients (58.5%). The male to female ratio was approximately 3:1. Majority of patients 32 (45.71%) had diabetes of >10 years duration. Foot and toe deformities affected majorly diabetics with moderately controlled diabetes mellitus and the study revealed that 40 patients (57.2%) had moderately controlled diabetes with blood sugar levels ranging from 160-200 mg/dl. The highest number of patients i.e. 29 patients (41.4%) who had foot/ toe deformities were on oral hypoglycaemic agents. Clawing of the toes (26 patients, 37.14% of patients), was the commonest morphological change in the architecture of the foot followed by Varus deformities (17 patients, 24.28% of patients). Nail changes in the form of hypertrophied and brittle nails affected 37 patients (52.85%). Conclusion:We concluded that team approach, adequate diabetic control combined with patient education about foot care and footwear will help prevent complications and improved quality of life of the patients suffering from diabetic foot and toe deformities.

Every drug manufacturer is legally bound to display the date of expiry on all pharmaceutical products. Excluding certain medicines such as nitroglycerin, insulin, epinephrine, and tetracycline, most medicines stored under reasonable conditions retain at least 70–80% of their original potency for at least 1–2 years after the expiration date, even after the container has been opened. The drug is likely to lose some potency after the expiration date, but it is not clear how much potency is lost over a certain period of time past expiration dates. Placing medication in a cool place, such as a refrigerator, will help it remain potent for many years. Even though both the American Medical Association and the Food and Drug Administration do not recommend the dosing of expired pharmaceuticals at this time, discussion of the issue is warranted in order to understand the potential behind some expired drugs. This review article studies the financial implications and reason for stock piling of unused and expired pharmaceuticals, health hazards, common and ideal ways of disposal of unused and expiry medications and the way forward.

COVID-19 has shaken up the world and these COVID times have allowed us to slow down, log out, switch off for a while and think about our real needs against greed. The ‘lockdown’ has provided us with an opportunity to pursue our hobbies and passion, to learn a new skill, to read your favorite books, watch movies which you have missed, to work-out which you missed doing due to paucity of time and to sit back and think about how to improve and make ourselves a better person. Most of us can work from home and if we are determined, we can cut down on our travel thus reducing air and water pollution in addition to a significant reduction in the number of road traffic accidents. The health crisis brought every one of us together and Corporate India shouldered its corporate social responsibility, reel heroes and cricket legends played their part well and Corona warriors led the war against the virus with grit and determination under the able leadership of a dynamic Prime Minister.

Introduction: Surgery for acute appendicitis is the most common surgery performed worldwide. Aim: This study was led to investigate the statistical attributes, occurrence, and patterns of Acute Appendicitis over a time frame of two years from Jan 2017 to Dec 2018 at a peripheral hospital in Maharashtra, India. It likewise contemplated the measurement of informative supplement in instances of Acute Appendicitis on Ultrasonography assessment and dissected the histopathology reports of the appendectomy specimens. Materials: We directed a retrospective analysis to evaluate the statistical highlights including the demographic features and seasonal variation of acute appendicitis in a peripheral hospital in Maharashtra, India over a time of two years from Jan 2017 to Dec 2018. Ultrasound reports of all cases worked for Acute Appendicitis were analysed. All carefully resected appendectomy specimens which were submitted for histopathological studies and histopathology reports were analysed. Results and Conclusion: The occurrence of Acute Appendicitis is increasingly common in males when contrasted with females. The most elevated rate happens in the age group of 20-30 years. Negative appendectomies were 18.68% and females were all the more regularly worked for negative appendectomies (12 out of 17 making it to 70.58%). The frequency is most noteworthy in the long stretches of October (15.94%) and November (13.04%).Ultrasonography of the abdomen uncovered a diameter of more than 6mm as a rule of acute appendicitis. In a perfect therapeutic world, we might want to ideally determine and get all patients having suspected Acute Appendicitis undergo appendicectomy without negative appendectomies yet a fine parity must be kept up between the potential dangers of negative appendectomy as opposed to inclining the patient to the probability of appendicular perforation at whatever point there is an analytic difficulty.