Objective: The aim of this comparative experimental study designed is analyze the possible changes in GH serum and lactate during the performance of resistance exercise-induced ischemia in young athletes. A possible outcome will be to promote greater strength gains and muscle hypertrophy during the training protocol.Design: This survey was conducted with 18 male football players 18 years of age. The athletes were divided into two groups; one group was subjected only to quadriceps exercises; the other group was subjected to quadriceps exercises associated with vascular occlusion. Levels of lactate and GH were observed before and after resistance exercise.Results: Comparing intergroup data, there were no statistically significant results. However, when comparing data within the groups, there was an increase in Group 2 obtained for both the lactate threshold and GH. Group 1 showed an increase in the lactate threshold, but a decrease in GH. Conclusions:This new method of resistance training should be analyzed, and further experiments are needed to optimize the protocol to reach optimum high intensity resistance training in young athletes.