This study aims to examine the effect of adding water extract of Sambiloto (Andrographis paniculata Ness) to drinking water on the performance and blood lipids profilem of cockerel  aged 0-7 weeks. This study was conducted in the village of Cepaka, Kediri, Tabanan, Bali. Using A total of 200 birds of aged 1 day old chick laying hens males.. The experimental design used was a Completely Randomized Design (CRD) with four treatments and five replications so that there were 20 units, each replicate using 10 chickens. The treatments were: (A) Drinking water without the addition of extract sambiloto leaf water, (B) drinking water with the addition of sambiloto leaf water extract 2 ml/l , (C) drinking water with the addition of sambiloto leaf water extract 4 ml/l and (D) drinking water with the addition of sambiloto leaf water extract 6 ml/L The variables observed in this study were performance, carcass, blood lipid profile, digestive tract microbes and economic aspec. The results showed that the administration of sambiloto  leaf water extract not significantly different (P>0.05) on ration consumption, drinking water consumption, final body weight, FCR, blood lipid profile, total coliform and E.coly and significantly different (P<0.05) on carcass percentage, carcass composition.