BACKGROUND AND OBJECTIVESAntenatally detected urinary tract abnormalities (ADUTA) are increasingly recognized. Our aims were to determine the incidence and outcomes of antenatally diagnosed congenital hydronephrosis in a large cohort.DESIGN AND SETTINGSWe recorded the number of total deliveries over 4 years at King Abdulaziz University Hospital (KAUH) between January 2008 and December 2011 from the number of nursery and neonatal intensive care unit (NICU) admissions.PATIENTS AND METHODSWe reviewed the records of 18 853 deliveries between January 2008 and December 2011 at KAUH, Saudi Arabia. ADUTA were recorded, and their postnatal medical records were reviewed for demographic and radiological data.RESULTSADUTA were diagnosed in 327 fetuses (1.7%). The commonest pathology was congenital hydronephrosis (n=313, 95.7%). Cystic renal anomalies were reported in 4 babies (1.2%), and 10 children (3.1%) were reported to have other renal anomalies, including duplex kidneys or a single kidney. A total of 240 babies with congenital hydronephrosis were followed up. Hydronephrosis resolved in 99 children (41.2%) within 2 months of birth. A total of 29 subjects had underlying renal anomalies (12.1%), including vesicoureteral reflux (n=12, 5%), pelvi-ureteric junction obstruction (n=14, 5.8%), and posterior urethral valve (n=3, 1.3%). The best predictor for nonresolving congenital hydronephrosis and underlying anatomical abnormalities was the anteroposterior diameter on the first postnatal scan. A cut-off point of 5 mm was found to be 83% sensitive in predicting nonresolving hydronephrosis, while 7 mm was 88% sensitive and 10 mm was 94% sensitive.CONCLUSIONSCongenital hydronephrosis is the commonest ADUTA. A large percentage resolved within 2 months of birth, but underlying anatomical abnormalities were found in 12.1%. All babies with antenatally detected hydronephrosis should be examined by ultrasound postnatally but further radiological investigations should only be performed for persistent significant AP dilatation ≥10 mm.

To analyze the clinical presentation, investigations, diagnosis and management of patients with Kawasaki disease seen at the two centers, an analytic study of data from the medical records of all patients of Kawasaki disease admitted to King Abdulaziz University Hospital and King Faisal Specialist Hospital and Research Centerwas done from January 2000 to June 2012. A total of 56 patients were included in the study with the mean age of 30.5 months (range from 2-132 months). Diagnosis and administration of intravenous immunoglobulin were performed after the mean of 8.4 days (ranged from 3-31 days). Twenty-eight patients had classical Kawasaki disease (50%) while the other 28 had incomplete Kawasaki disease (50%). A wide variety of clinical symptoms and signs were found in our patients. Thrombocytosis was detected in 32 patients at presentation. Coronary artery lesion was detected in 27 patients; 13 from classical Kawasaki disease group and 14 from incomplete Kawasaki disease group. Out of these, 20 had thrombocytosis at presentation, making it a significant risk factor for the development of coronary artery lesion (p-value = 0.013). The percentage of incomplete Kawasaki disease is quite high in our patients. Epidemiological studies are needed, and National Kawasaki Disease Awareness Program, aiming at avoiding delays in diagnoses, is suggested.

AbstractsConclusions 88 transfers for gastroschisis were conducted over the period. 91% babies were kept within region and transferred within an average time of 80 min in keeping with the network guideline. There have been no patient related clinical incidents. Purpose Antenatally detected urinary tract abnormalities (ADUTA) are increasingly recognized. Our aims were to determine the incidence and outcomes of antenatally diagnosed congenital hydronephrosis in a large cohort. Methods We reviewed the records of 18,853 deliveries between January 2008 and December 2011 at King Abdulaziz University Hospital, Saudi Arabia. ADUTA were recorded and their postnatal medical records were reviewed for demographic and radiological data. Results ADUTA were diagnosed in 327 fetuses (1.7%). The commonest pathology was congenital hydronephrosis (n=313, 95.7%). Cystic renal anomalies were reported in four babies (1.2%) and 10 children (3.1%) were reported to have other renal anomalies, including duplex kidneys or a single kidney. Two-hundred and forty babies with congenital hydronephrosis were followed-up. Hydronephrosis resolved in 99 children (41.2%) within 2 months of birth. Twentynine subjects had underlying renal anomalies (12.1%), including vesico-uretral reflux (n=12, 5%), pelvi-uretric junction obstruction (n=14, 5.8%) and posterior urethral valve (n=3, 1.25%). The best predictor for non-resolving congenital hydronephrosis and underlying anatomical abnormalities was the AP diameter on the first postnatal scan. A cut-off point of 5 mm was found to be 83% sensitive in predicting non-resolving hydronephrosis, while 7 mm was 88% sensitive and 10 mm was 94% sensitive. Conclusion Congenital hydronephrosis is the commonest ADUTA. A large percentage resolved within 2 months of birth, but underlying anatomical abnormalities were found in 12.1%. All babies with antenatally detected hydronephrosis should be examined by US postnatally but further radiological investigations should only be performed for persistent significant AP dilatation ≥10 mm. MAJOR BIRTH DEFECTS AMONG BABY, S BORNS IN QATAR