Tlie Granada T.V. filtn "The Drug Takers" was made to present fads about drug abuse in an unsemational, rational way. The effects of the film on a sample of school children was assessed using a questionnaire and the main finding was that the fitm had no significant effect on any of the attitudes assessed. Possible reasons for this are examined, which imply a different approach to future educational projects in this field.

A previously published study regarding the outcomes of oesophagectomy at a provincial hospital identified issues with perioperative care (Al-Herz et al 2012). The aim of this study was to evaluate the effect of changes in management at the institution concerned. This was a cohort study which compared the outcomes of 30 patients undergoing oesophagectomy before the unit audit and 30 patients after it. Demographics, operative details, recovery parameters, and oncological data were collected retrospectively. There was a significant reduction in the use of intravenous fluid, both intraoperatively (6.6 vs 3.3L, P < 0.0001) and during the first 24 hours (9.2 vs 5.5L, P < 0.0001). Patients were extubated three days earlier (P < 0.001) after the audit, and the percentage of patients requiring tracheostomy was smaller (26.7% vs 0%, P = 0.003). The length of total hospital stay was shorter (15 vs 13 days, P = 0.035). We conclude that the publication of a unit audit changed perioperative practice and resulted in a significant improvement in the short term outcomes after oesophagectomy.

Many instances of regular cyclic or periodic psychiatric and clinical syndromes have been reported (Richter, 1957). The duration of each cycle varies from 2 days to 18 months but is usually constant in a given subject and bears no relationship to external factors. Presumably they have their origin within the body, and a disturbance of endocrine function has been suggested in many cases. Some women show cycles corresponding to the menstrual rhythm, the abnormal phase preceding or accompanying the menstrual flow.

Reports of significant changes in water and electrolytes during recovery from depression may provide insight into important physiological factors in depressive illnesses. Brown et al. (1963) demonstrated an increase in the extracellular fluid volume in 22 of 28 patients suffering from primary depressive disorders treated with E.C.T. or imipramine. The findings of these authors, which were discussed in relation to previous work on sodium metabolism and water balance in depressive disorders, were thought to support the idea of a shift of fluid from intracellular to extracellular spaces during the response to treatment. Coppen and Shaw (1963) found an increase in total body water, extracellular fluid and a decrease in the residual sodium space on recovery from depression.

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