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Eleven Ia or B-cell specificities of rhesus monkeys have been serologically identified. They are probably all controlled by the RhLa complex, but, according to results of a large population and family study, only five or six can be placed in a segregant series, designated as Ia1. Data from recombinant offspring in two rhesus families place the Ia1 locus in the close vicinity of the D or major MLC locus within RhLA. The genetic control of the Ia antigens not defined by the Ia1 locus has not yet been clarified.

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