Ensuring the proper thermal performance of a building’s envelope upon reception is an important stage in the life cycle of the building. Several methods already exist for this purpose, and continue to be improved, such as co-heating, ISABELE, EPILOG, QUB and SEREINE. All these methods follow the common protocol consisting of heating the measured building. These measurement protocols quantify the dynamic evolution of interior and outdoor temperatures, and the thermal power injected into the building and these data are used in calibration algorithms to determine, by an inverse method to deduce a heat loss value. These methods require a difference of a few degrees between the interior and the exterior which can cause in summer periods a risk of damaging the building, as the outside temperature may already be high. The objective of this work is to explore the possibility of determining the intrinsic thermal performance of a building’s envelope in the summer period using a cooling system. This work leans on an experiment of a square meter scale cell and explore the capacities and limitations of the method at this scale by varying several stress parameters of the enclosure. Results in cooling mode are also compared to heating mode.