Introduction: Oocyte cryopreservation is used to preserve a woman's oocytes. It is a technique that enables females to postpone pregnancy to a later date, for reasons such as medical (cancer treatment) or in some countries for social reasons such as employment or study.Patient concerns and diagnoses: Cryopreservation of oocytes in ten young, single, and virgin women with malignant disease Interventions: Transabdominal follicular aspiration for oocyte retrieval and cryopreservation Outcome: A total of 148 oocytes were retrieved. The number of mature oocytes retrieved were 112. The operative time ranged from 45 minutes to 120 minutes. None of the patients had complications after the procedure. Conclusion:Transabdominal ultrasound-guided aspiration can be the modality of choice for women with malignant disease, especially unmarried/ virgin women who desire to retain intact hymen for cultural reasons.