No abstract

The results of local low-dose thrombolytic treatments of 564 peripheral arterial occlusions were as follows: Embolic occlusions up to 6 weeks could be removed in 72.7%, the longer lasting occlusions in 42.3%. Thrombotic occlusions lasting up to 6 months were successfully treated in 58%, still older ones in 36.2%. The cumulative patency after 5 years was 89.5% in embolic and 58.8% in thrombotic occlusions. Therefore, the differential therapy of acute peripheral ischemia has to be thought over anew together with the vascular surgeons.

The efficacy of and tolerance to ticlopidine, a platelet inhibitor, in preventing progression of obliterative arterial disease was compared with that of a placebo in a double-blind and randomized trial in 43 patients (22 on placebo, 21 on ticlopidine) over a period of one year. The course of the disease in both groups was assessed by serial angiography of the lower limbs, both at the beginning and at the end of the study. There was a significantly reduced progression in the ticlopidine group (P less than 0.01). The results support the hypothesis that platelets are of great importance in the progression of arteriosclerosis and that inhibition of platelet function is an effective principle of prevention. Ticlopidine in this respect is an alternative to the use of acetylsalicylic acid.

No abstract

The authors tested the clinical efficacy of the malleotrain bandage in a clinical field trial on a very large mixed patient material from 1980 onwards. The patient material included a total of 350 cases of ankle joint injuries with partial and total fibular ruptures of ligament, ruptures of the inferior tibiofibular joint, conditions after malleolar fractures as well as posttraumatic or postoperative swelling.--It was found that the malleotrain bandage achieved subsidence of swelling of the periarticular soft parts, relief of complaints and considerable normalisation of functioning, within an unusually short time and without medication or other local measures.--Patients who had been operated on for complete rupture of fibulotalar ligament were given by Lippay the malleotrain bandage only, after having immobilised the malleolus by means of a plaster cast for 10 days, without any disadvantages in respect of healing and subsequent stability.--Blandfort had even treated complete lateral ankle joint ligament ruptures conservatively with the malleotrain bandage only and had thus achieved cure resulting in stable ligaments.--The ability to work and to resume sports activities returned on the average two weeks earlier than with plaster cast immobilisation.