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Haemodynamic after Total Heart Replacement by an Incorporated Double Chamber Blood PumpSummary. The paper reports on haemodynamic observations in 20 calves surviving total heart replacement by an incorporated double chamber blood pump for more than 10 h. The following parameters are registered:--pressures in both atria and vena cava inferior, --pressures in aorta and pulmonary artery, --pressures in both artificial ventricles, --pressures in the pneumatic driving system, --perfusion volumes and AVDO 2. It is demonstrated that the artificial blood pumps are able to obtain a perfusion volume sufficient for the animal's vitality.A sufficient regulation can be achieved by varying the driving system and by the so called Starling-mechanism of the artificial heart.In the long time surviving animals an increase of the right atrium pressure, and of the perfusion volumes is found while total peripheral resistance decreases.To explain these observations, disturbances of the neurohumoral circulatory control by the action of the artificial pumps or the development of sepsis are discussed.

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