The current chapter provides comprehensive data on the tumours derived from the lymphoid tissues that are most commonly affecting the lymph nodes. We discuss the principles of the current classification of lymphoid neoplasia, its clinical relevance, and the possible use of different prognostic factors. For every disease entity, up‐to‐date information on the specific clinical presentation and site of involvement, morphology, including different morphological variants, immunophenotype and genetics is offered. Basically, the lymphoid tumours consist of Hodgkin's disease and non‐ Hodgkin's lymphomas and the latter are subclassified into B‐ and T‐cell lymphomas, according to their putative cell of origin. On the basis of the literature and our own experience we review the relevance of specific lymphoma features for the diagnosis and clinical outcome of lymphoma patients.
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