Summary Serum samples from 254 non vaccinated and apparently healthy dogs of local breeds in Nsukka environs, Nigeria were examined for the presence of antibodies to rabies virus by haemagglutination‐inhibition technique. The prevalence rates of rabies antibodies in, less than 3 months, 3—6 months, and over 6 months old dogs were 17.5 %, 7.3 % and 22.8 % respectively, and overall 16.1 % in the dog population. This was the first documented report of rabies antibodies in non vaccinated dogs in Eastern Nigeria. The results were discussed with respect to the epidemiology of prototype rabies and rabies‐related viruses. It was suggested that the antibodies were most probably due to the non virulent prototype rabies or rabies‐related virus strains. 83.9 % of susceptible dogs in the population suggested a mandatory regular a vaccination of all dogs in interest of public health and control of the disease. The study highlighted the need for more studies on epidemiology of rabies and rabies‐related viruses in Nigeria. Zusammenfassung Seroepidemiologische Untersuchung von Tollwut‐Antikörper‐Titern in nichtgeimpften Hunden in der Gegend von Nsukka, Nigeria Serumproben von 254 nichtgeimpften und offensichtlich gesunden Hunden aus der Gegen von Nsukka, Nigeria wurden mit dem Hämagglutinationshemmungstest auf den Gehalt von Tollwut‐Antikörpern untersucht. Die Antikörper‐Prävalenzrate war bei Hunden im Alter unter 3 Monaten 17,5 %, von 3–6 Monaten 7,3 %, über 6 Monaten 22,8 % und in der Gesamtpopulation 16,1 %. Die Arbeit stellt den ersten Bericht über die Verteilung von Tollwut‐Antikörpern bei nichtgeimpften Hunden in Ost‐Nigeria dar. Die Ergebnisse werden hinsichtlich der Epidemiologie des Tollwutvirus selbst sowie verwandter Viren diskutiert. Man vermutet, daß die Antikörper höchstwahrscheinlich auf nichtvirulente Tollwutstämme oder verwandte Viren zurückzuführen sind. Da 83,9 % der Hundepopulation empfänglich sind, wird im Hinblick auf die Volksgesundheit Impfpflicht und Kontrolle der Seuche empfohlen. Die Untersuchung beleuchtet die Notwendigkeit weiterer epidemiologischer Studien über Tollwut und tollwut‐verwandte Viren in Nigeria.
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