Ten patients with post-kala-azar dermal leishmaniasis (2 females, 8 males-aged 17-47 years) are described. Two of them had macular lesions in which very few Leishman-Donovan bodies were seen and who responded well to treatment with stibophen. Five patients had both macular and nodular lesions, Leishman-Donovan bodies being present in nodules but not in macules. Treatment with stibophen caused partial regression of nodules. Nodular lesions were found in three patients, who did not have macules. They contained numerous Leishman-Donovan bodies and treatment produced only temporary improvement. The variable response to treatment with stibophen may have been due to differences in parasitic load. The difficulty in distinguishing this disease from leprosy is discussed.
555 clinically suspected cases of dermatomycoses were studied for causative fungi and their detailed clinical manifestations. The fungi were demonstrated on routine KOH mount and/or by culture in 464 cases (83.6%). Tinea corporis was the predominant fungal infection (30.6%) and T. rubrum was the main etiologic agent. Favus (T. schoenleini) was found only in cases from Jammu and Kashmir valleys. There was a high incidence of tinea capitis among children. Trichophyton tonsurans was isolated in cases of tinea corporis, tinea cruris, and tinea pedis. Trichophyton ferrugineum and T. verrucosum were isolated from cases of tinea capitis; and Microsporum gypseum was isolated from tinea cruris infections.
Reactive perforating collagenosis is a recently-recognized entity, in which a series of epidermal changes lead to elimination of altered collagen bundles through the transepidermal route. Clinically the disease is manifested by the appearance of asymptomatic papules which develop a central umbilication and then disappear spontaneously in 6–8 weeks. A necrobiotic change of collagen in response to trauma in genetically-predisposed individuals is considered to be of etiologic significance. The authors describe a typical case in which a distinct improvement in summer months was regularly recorded for the last 20 years.
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