IT has been shown in the preceding paper [Robson & Schild, 1937] that under certain conditions vasopressin inhibits the longitudinal muscle of the cat's uterus in situ, but that it has no effect on the isolated organ suspended in Ringer-Locke solution. The inhibition in situ was observed in spayed cats treated with the ovarian hormones, but not in untreated spayed cats or in animals in the later stages of pregnancy. The question arose whether this inhibition, obtained only in the intact animal and then under certain conditions, might be a consequence of the constriction of the blood vessels of the uterus produced by the pressor hormone. In this connexion the more general problem arose whether vasoconstriction and vasodilatation of the uterine blood vessels produced secondary changes in the state of contraction of the uterine muscle and also whether contraction of the muscle affects the blood flow through the organ.The present research deals with these points. The blood flow through the uterus and the contractions of the organ were simultaneously registered and the effects of various drugs were investigated.
METHODSThe experiments were done on cats under chloralose aneesthesia. A preliminary removal of the stomach, intestine and spleen was always performed.The contractions of the longitudinal and the circular muscle of the uterus were registered by the methods previously described [Rob so n and Schild, 1937].The blood flow through the uterus was estimated in the majority of experiments by means of a constant rate perfusion method. In others oncometers were used.
A modified procedure for infiltrating the coeliac plexus for the treatment of chronic pain syndromes is described. The injection of the analgesic is made through a fine needle introduced via a transabdominal approach under CT guidance. The advantages of this technique, compared with the dorsal approach, are a more accurate placement of the solution and the ability to carry out this procedure in very sick patients. No complications have been observed.
Radiation dose to the ocular lens, parotid gland and thyroid gland during fluoroscopy-guided DCP was 25 times higher than during diagnostic dacryocystography. The radiation dose to radiosensitive head and neck organs and tissues during fluoroscopy-guided DCP is much below the threshold dose for ocular lens cataract.
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