A powerful cold auto anti-I has been found that is strongly inhibited
by hydatid cyst fluid and inhibited to a varying extent by all of the 181 human
saliva samples tested. The investigation showed that the inhibition effect was
specific for I and that water soluble I blood group substance must be responsible.
No correlation could be found between the concentration of I substance in the
saliva and the presence of ABH, Lewis or Sda substances. The amount of salivary I
substance secreted appears to be a constant feature of the individual. Infants at
birth and i adults have high concentrations of I substance in their saliva and the
amount of I substance present does not reflect the I status of the red cells.
Our results showed that two rare features of TS's RBCs, NOR polyagglutination and St(a) glycophorin, are inherited independently, and that NOR+ RBCs contain neutral glycolipids with an abnormal oligosaccharide structure, most likely terminated with alpha-galactosyl residues.
Abstract. A case is reported of a young male patient who developed autoimmune haemolytic anaemia. During the acute phase, anti‐Kpb was detected in his serum and his antigens of the Kell system were markedly depressed. On remission, the antibody disappeared and the Kell antigens were normally expressed.
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