Severe poisoning and deaths after intake of ethylene glycol in man were described for the first time in 1930 (6,17,37). During the 1940s and 50s several reports of similar cases of poisoning were published. The mortality was throughout very high (41). The relevant literature and the current principles of treatment were reviewed by Friedman et al. in 1962 (12). Haemodialysis for the purpose of removing the toxic substance and possibly its metabolities hasbeentriedinafewcases (11, 12,41). I t has also been used in the treatment of acute renal failure secondary to ethyleneglycol poisoning (1 1, 12, 27, 29, 41). A short account will be given here of the metabolism and toxicity of ethylene glycol. A case of ethylene-glycol poisoning with severe toxic manifestations referable to the brain and the kidneys will then be presented. The cerebral disorder was studied by repeated electroencephalographic recordings. The patient was dialysed three times. He recovered.
SummaryThe absorption of oxygen administered into the intestine of newborn anoxic kittens has been investigated. The results indicate that the oxygen content of the blood of markedly anoxic newborn kittens increases during rectal administration of oxygen.
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