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Localization procedures are required in catecholamine-producing tumors after clinical and biochemical confirmation. Computed tomography, ultrasound and/or ¹³¹I-metaiodobenzylguanidine (¹³¹I-MIBG) scintigraphy was performed in patients with pheochromocytoma, neuroblastoma and metastases of carcinoid tumors. Whereas computed tomography and ultrasound reflect morphological abnormalities, adrenomedullary scintigraphy depends on hormonal activity and other factors. ¹³¹I-MIBG scintigraphy has the advantage of detecting extraadrenal, multilocular and malignant pheochromocytomas. Especially small lesions and tumor tissue in bone marrow in children with neuroblastoma can be visualized more easily.

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51 surgically treated cases with hormone-producing tumours of the adrenal cortex are evaluated for the reliability of preoperative localisation of diagnostic measures and postoperative results. 6 patients were children. The group contains 14 cases of Conn's syndrome, 32 cases of hypercortisolism, including 3 children, and 5 cases of AGS, 3 of which were children. The recommended work-up procedure is initiated by ultrasonography and followed by CT, possibly in combination with adrenal scintigraphy. This combination of a morphological and functional investigation established the correct diagnosis in all 51 cases. Laboratory values returned to normal levels in all cases, phenotypical aspects normalised in most cases. Deaths and complications occurred only in hypercortisolism and AGS.