Background & aim: Marital commitment is the strongest and most stable factor predicting the quality and stability of married life. The aim of this study was to investigate the role of flourishing, self-compassion and cognitive emotion regulation strategies in predicting marital commitment in nurses. Methods: This was a descriptive and correlational study. The statistical population included the nurses working in Imam Reza Hospital in Kermanshah in 1400, among them 210 nurses were selected by available sampling method. Participants completed the Adams, Jones questionnaire of marital commitment, Biswas-Diener questionnaire of flourishing, Neff questionnaire of Self-Compassion and Garnefski et al questionnaire of cognitive emotion regulation. The research data were analyzed using SPSS-25 through descriptive statistics (mean and standard deviation) and Inferential statistics (Pearson correlation, canonical correlation analysis (CCA) and multiple regression methods) Results: CCA results indicated that there was a significant correlation between the marital commitment and variables of flourishing, self-compassion and cognitive emotion regulation strategies in the nurses (p<0.001). Also, results of regression analysis revealed that 28% of the variance of the marital commitment variable could be predicted by predictor variables of flourishing, self-compassion and cognitive emotion regulation strategies. Conclusion:It can be said that flourishing, self-compassion and cognitive emotion regulation strategies play a role in increasing marital commitment. Therefore, marital commitment can be increased by improving flourishing, self-compassion and teaching cognitive emotion regulation strategies.