The in-plane resistivity rho and thermal conductivity kappa of the FeAs-based superconductor KFe2As2 single crystal were measured down to 50 mK. We observe non-Fermi-liquid behavior rho(T) approximately T{1.5} at H{c{2}}=5 T, and the development of a Fermi liquid state with rho(T) approximately T{2} when further increasing the field. This suggests a field-induced quantum critical point, occurring at the superconducting upper critical field H{c{2}}. In zero field, there is a large residual linear term kappa{0}/T, and the field dependence of kappa_{0}/T mimics that in d-wave cuprate superconductors. This indicates that the superconducting gaps in KFe2As2 have nodes, likely d-wave symmetry. Such a nodal superconductivity is attributed to the antiferromagnetic spin fluctuations near the quantum critical point.

Background: Tumor IL17-producing (IL17A þ) cells infiltration has different prognostic values among various cancers. The objective of this study was to assess the effect of IL17A þ cells in gastric cancer. Patients and methods: The study included two patient cohorts, the Cancer Genome Atlas cohort (TCGA, n ¼ 351) and the Zhongshan Hospital cohort (ZSHC, n ¼ 458). The TCGA and ZSHC were used for mRNA-related and cells infiltration-related analyses, respectively. The roles of IL17A mRNA and IL17A þ cells in overall survival (OS), response to adjuvant chemotherapy (ACT), and immune contexture were evaluated. Another independent cohort was included to identify the correlation between mRNA of IL17A and IL17A þ cells infiltration (the preliminary Zhongshan Hospital cohort, PZSHC, n ¼ 21). Results: The infiltration of IL17A þ cells was positively correlated with the expression of IL17A mRNA (Spearman's q ¼ 0.811; P < 0.001). High IL17A mRNA expression and intratumoral IL17A þ cells were correlated with improved OS and remained to be significant after adjusted for confounders. Patients with TNM II/III disease whose tumor present higher intratumoral IL17A þ cells or lower peritumoral IL17A þ cells can benefit more from ACT. Elevated IL17A mRNA expression and increased intratumoral IL17A þ cells infiltration was associated with more antitumor mast cells and nature killer cells infiltration and less pro-tumor M2 macrophages infiltration. High IL17A mRNA expression represented a Th17 cells signature and immune response process and was correlated with increased cytotoxic GZMA, GZMB, IFNG, PRF1, and TNFSF11 expression. Conclusions: IL17A mRNA expression and intratumoral IL17A þ cells infiltration were correlated with antitumor immune contexture. IL17A þ cells infiltration could be used as an independent prognostic biomarker for OS and predictive biomarker for superior response to ACT, and further prospective validation needs to be conducted.

The in-plane resistivity and thermal conductivity of the heavy-fermion superconductor Ce 2 PdIn 8 single crystals were measured down to 50 mK. A field-induced quantum critical point, occurring at the upper critical field H c2 , is demonstrated from the ðTÞ $ T near H c2 and ðTÞ $ T 2 when further increasing the field. The large residual linear term 0 =T at zero field and the rapid increase of ðHÞ=T at low field give evidence for nodal superconductivity in Ce 2 PdIn 8 . The jump of ðHÞ=T near H c2 suggests a first-order-like phase transition at low temperature. These results mimic the features of the famous CeCoIn 5 superconductor, implying that Ce 2 PdIn 8 may be another interesting compound to investigate for the interplay between magnetism and superconductivity. The interplay between magnetism and superconductivity has been a central issue for heavy-fermion superconductors [1], high-T c cuprates [2], and iron pnictides [3]. Among them, one particularly interesting case is the heavy-fermion superconductor CeCoIn 5 , with T c ¼ 2:3 K at ambient pressure [4]. Its superconducting gap has d-wave symmetry [5,6]. While there is no static magnetism in CeCoIn 5 at zero field, a field-induced antiferromagnetic (AF) quantum critical point (QCP) has been clearly demonstrated by resistivity and specific heat measurements [7,8]. Initially, it was very puzzling why the AF QCP is located right at the upper critical field H c2 .Meanwhile, the observations of first-order phase transition at low temperature and H c2 and a second magnetization and specific heat anomaly well inside the superconducting state have been interpreted as the signature of a Fulde-Ferrell-Larkin-Ovchinnikov (FFLO) superconducting state [5,[9][10][11][12]. The novel FFLO state with broken spatial symmetry was predicted in the 1960s [13,14], but it has never been experimentally verified before. The possible FFLO state at the low-temperaturehigh-field (LTHF) corner of the H À T phase diagram of CeCoIn 5 has stimulated extensive studies [15].More recently, NMR, neutron scattering, and muon spin rotation ( SR) experiments have provided clear evidence for a field-induced magnetism in this LTHF part of the phase diagram [16][17][18][19][20][21]. It was identified as a spin-density wave (SDW) order with an incommensurate modulation Q ¼ ð0:44; 0:44; 0:5Þ. Interestingly, this SDW order disappears in the normal state above H c2 , showing that magnetic order and superconductivity in CeCoIn 5 are directly coupled [16,17]. While this has nicely explained the field-induced AF QCP at H c2 [7,8], the physical origin of this LTHF superconducting Q phase is still under debate. For example, Yanase and Sigrist have suggested that the incommensurate SDW order is stabilized in the FFLO state by the appearance of the Andreev bound state localized around the zeros of the FFLO order parameter [22]. Aperis, Varelogiannis, and Littlewood have argued that the Q phase is a pattern of coexisting condensates: a d-wave singlet superconducting state, a staggered -triplet superconducting s...