Oral diseases caused by various microorganisms are common around the world. Scientific research has now been focusing on novel medicines to overcome bacterial resistance and antibiotics side effects; therefore, the current study was designed to assess the efficacy of certain antibiotics, toothpaste, and medicinal plant extracts (Ajuga bracteosa and Curcuma longa) versus the bacterial pathogens isolated from the human oral cavity. A total of 130 samples were collected from Khyber Teaching Hospital Peshawar, Pakistan, among those 27 species isolated, and eight bacterial species were identified from the samples. Among all the bacterial species, Staphylococcus aureus (29.62%) and Proteus mirabilis (22.2%) were found to be more prevalent oral pathogens. In comparison, the least pervasive microbes were Proteus vulgaris, Shigella sonnei, Escherichia coli and Aeromonas hydrophila. The study also suggested that dental problems were more prevalent in males (41-50 years of age) than females. Among the eight antibiotics used in the study, the most promising results were shown by Foxicillin against A. hydrophila. The survey of TP1 revealed that it showed more potent antagonist activity against Proteus vulgaris as compared TP2 and TP3 that might be due to the high content of fluoride. The Curcuma longa showed more significant activity than Ajuga bracteosa (Stem, leaves and root) extracts. The data obtained through this study revealed that antibiotics were more effective for oral bacterial pathogens than toothpaste and plant extracts which showed moderate and low activity, respectively. Therefore, it is suggested that the active compounds in individual medicinal plants like Curcuma longa and Ajuga bracteosa could replace the antibiotics when used in daily routine as tooth cleansers or mouth rinses.

Objective COVID-19 resulted in dentistry being declared high-risk occupation due to the mode of the spread of the virus. This resulted in partial and complete closure of dental practices around the world, reducing revenue of practitioners. Hence, study aims to evaluate financial impact on dental practitioners in Pakistan and UAE. Materials and Methods A questionnaire-based cross-sectional study was conducted from July 2020 to January 2021. It involved questions relating to demographics and financial challenges faced, associated with change in standard operating procedures due to pandemic. The descriptive statistics were expressed as frequency and percentage. Statistical analysis was performed by Chi-square test or Fischer's exact test. Results In total, 427 respondents participated in the study. Approximately half (55.7%) of the respondents had their practices shut down, while 89.9% observed decrease in patient flow. The majority (82.2%) of respondents had to buy personal protective equipment (PPE), whereas 66.7% had to pay a high cost for that. Almost 87.3% of respondents reported having experienced financial constraints because of the pandemic related changes to the practice. Moreover, 27.8% reported staff being laid off, which were mostly due to monetary constrictions. Conclusion Dental professionals faced a considerable impact on their practice and financial situation due to pandemic. Policies must be made to support such professionals in times of emergency who are at higher risk of being most affected with respect to health and finances.