Background: Medication errors occur at any point of the medication management process involving prescribing, transcribing, dispensing, administering and monitoring, have been reported to account for approximately one-quarter of all healthcare errors.. So, the aim of this study is to identify the strategic reduction of medication errors in emergency department at Elmabarha hospital Port Said city. Subjects and Methods: A descriptive research design was utilized. The subjects number 110 health care staff doctors, nurses & technical. Data was collected by using checklist tool .Results: Medications are safely and accurately dispensed according to laws and regulations" was the highest dimension that done (44.5 %). While the lowest dimension was "Medications are prepared safely" (17.3 %). Finally according to the total percentages 62.7 inspect Medication error with moderate degree. Conclusion:it was concluded that there is a statistical difference between all healthcare providers in most of dimensions as Effective planning and management of medication,