HighlightsHepatoid carcinoma of the ovary is rapidly progressing rare epithelial ovarian tumor.The term ‘hepatoid’ refers to the morphological resemblance with hepatocellular carcinoma.Final diagnosis is made via positive staining for alpha fetoprotein along with immunohistochemistryCombination chemotherapy can be considered superior over the targeted agents while treating this tumor.

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Background: Limited research has been performed for treating gynecological disease conditions using paleodiet intervention. It is in demand to conduct many randomized controlled trials to prove its effectiveness. This review indicates one of the most important literature gaps in gynae-oncology. Paleo nutrition has recently emerged as a treatment option in conditions related to gynecology, and such potential benefits are indicated in few short-term clinical trials and case reports related to gynecological cancers and malignancies.Objective: This meta-analysis is aimed to address the importance of nutritional intervention, with emphasis on paleo nutrition, in treatment of gynecological cancers, pre-malignancy conditions, and post-operative recovery in women.Materials: PubMed, Scopus, SciPubs, Mayo Clinic, Cochrane Library, Covance Laboratory and ASRM databases were used for collecting data in the form of case reports, research articles, reviews, clinical trials, journals, and books.Design: Out of 400 publications, 7 are shortlisted for their relevance to gynecological oncology and paleo nutrition interventions. Case reports and short-term clinical trials between year 2000-2020 are included for comparative analysis of Paleodiet and its variants with other nutritional interventions. Results:There is no scientific data that has been reported on genetic and molecular impacts of paleo-nutrition on gynecological cancers. Clinical reports suggest significant improvement through paleodiet intervention in anthropometric markers and metabolism in pre-treatment and post-treatment examination of patients of gynae-oncology. Very limited data is available for comparative analysis of paleodiet and other dietary interventions. Conclusion:Paleo nutrition is an under-researched future intervention and has a potential to impact treatment strategies for gynecological patients. A large volume of randomized controlled trials for each ethnic group can help manage the cancer burden globally.

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Primary pulmonary synovial sarcoma is a rare lung tumor and has mesenchymal origin. It is difficult to diagnose clinically and should be differentiated from other primary and metastatic lung tumors. The definitive diagnosis should be made via careful histopathological evaluation along with immunohistochemistry. Cytogenetic studies detect SYT-SSX-1 variant which has got diagnostic and prognostic value. The disease has poor outcome and complete cure is difficult to achieve. We hereby report a case of 40 years old female who was diagnosed and treated for metastatic primary pulmonary synovial sarcoma at Atomic Energy Cancer Hospital, NORI.