A systematic review of herpes zoster incidence and consensus recommendations on vaccination in adult patients on systemic therapy for psoriasis or psoriatic arthritis: from the medical board of the national psoriasis foundation.

Background Pellagra is a nutritional disease resulting from a deficiency of vitamin B3 (niacin) primarily due to corn consumption, especially in developing countries, but in developed countries, it can occur secondarily as a consequence of chronic alcoholism, malabsorption, certain drugs, and bariatric surgery. ResultsWe present a case of a 32-year-old woman from a rural area in Zanzibar who was a heavy alcohol consumer and came in with features suggestive of pellagra. ConclusionOur therapeutic approach consisted of niacin 500 mg once daily and betamethasone + salicylic acid ointment twice a day until lesions resolved and showed noticeable improvement.

Background Keloids are reported to be amongst the common conditions seen in the pigmented skin of African origin with an estimate of about 15 times more compared with other races. They seldom resolve spontaneously, have a poor response to treatment and pose enormous impact on quality of life (QoL) in affected individuals. Aesthetic discomfort, depression, low self‐esteem and some degree of isolation increase the burden of the disease. Methods This hospital‐based cross‐sectional study was conducted at the Regional Dermatology Training Centre in Northern Tanzania. A total of 117 patients with keloid older than 18 years attended the skin clinic from October 2017 to April 2018. Data were collected using disease‐specific structured questionnaire and all were assessed using the Dermatology Life Quality Index (DLQI) Questionnaire. Results The mean DLQI for this population was 8.3 ± 7.4 reflecting a moderate impairment. The QoL seemed to be influenced by the number of keloids, duration of disease and the presence of symptoms. It was mainly seen in young adults with a median age of 29 years (range: 18–88 years). There was no significant sex predilection. Trauma as an inciting event was reported in 42%. Conclusion Keloid patients with pigmented skin of African descent in Northern Tanzania have a moderate impairment in the QoL.

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