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The relationship between economics and sub-regionalism remains relatively unexplored, particularly in the Asia-Pacific context. This article seeks to broaden the comprehension of various dimensions of this relationship. One of the focuses is to understand the circumstances in which sub-regional institutions have come to be defined as components of economic development in Southeast Asia. Another is to develop a more nuanced approach to regional studies, one that recognizes that institutional changes can occur in many forms, like Historical Institutionalism. This paper’s starting point is on the emphasis that institution is a social construction: political contestations between the social forces in the domestic often influences how state shaped regional institutions that would serve their interest. It uses the critical juncture framework championed by the Historical Institutionalist approach during that particular period to produce divergent outcomes. This study uses BIMP-EAGA to provide some grounds for optimism on the relationship between institutional changes and economic development in the region. Keywords: Historical Institutionalism, critical juncture, economic development, institutional changes, sub-regional institutions, and BIMP-EAGA

cleredema of Buschke is a rare pathological disorder of connective tissue, which is characterized by a woody, diffuse induration of the skin, most often in the upper extremities. We report an extremely rare complication of post-streptococcal infection in a six-year-old male complaining of gradually progressing, painless skin thickening and tightness which was preceded by a one-month history of fever, cough, and tonsillitis. By reporting this case, we hope to contribute to the creation of a database for future research aimed at better understanding the incidence, pathophysiology, and management of this extremely rare complication.

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