Introduction Acute-on-chronic liver failure (ACLF) is a serious complication of liver cirrhosis which presents with hepatic and/or extrahepatic organ failure and often needs admission to an Intensive Care Unit (ICU). This condition typically needs organ support and carries a high mortality rate. ICU care may not benefit these patients. There are many scores to assess prognosis in these patients, such as the Model for End-stage Liver Disease (MELD) score, the MELD score refined to take into account serum sodium level (MELD-Na), the chronic liver failure organ failure (CLIF-OF) score, the CLIF Consortium acute-on-chronic liver failure (CLIF-C ACLF) score and the Child-Turcotte-Pugh classification. This study was conducted to compare CLIF-C ACLF and MELD scores for selecting patients at risk of high mortality, as ICU care to these patients in the absence of liver transplantation may be of no value.
BackgroundMalnourishment has been linked with increased morbidity and mortality among critically ill patients. The current study aimed to assess the factors contributing to the interruption of enteral nutrition so that preventive measures can be formulated to avoid the malnourishment of critically ill patients.
In society, the word criticism has always been considered a negative attitude in literature, its meaning is different. Interpretation and explanation of any work of art is not criticism. Just as Urdu literature has developed a lot, criticism has also introduced new trends, one of the branches of linguistics is stylistics. The word style is not new in literature. Writing style for it. Words like language and statement are taken as synonyms. Stylistic criticism is objective and analytical. In which the phonetics of the author's style of writing. Semantic. Syntactic and lexical reviewIt is taken so that the value and dignity of this writing can be properly estimated.
Mahir-ul-Qadri was born in the district of UP, India in 1906. After the establishment of Pakistan, he first came to Lahore and then migrated to Karachi. He started his literary career at the beginning of summer. He was accessible. He was a multi-lingual person. His memory was very strong. As a result of this, there was diversity in the knowledge and breadth of Purana on various topics. Mahir-ul-qadri is one of the few personalities who earned a name in literature, unfortunately, Mahir-ul-Qadri could not get the position he deserved. Mahir al-Qadri's study was very extensive, it can be estimated from the fact that he used to consult with the writers and scholars of that time to research a single word. For the purpose of research, he read many books. He was studying. And if someone raised an objection to him regarding a mistake, he would accept it with an open heart and would not give any opinion about any writing without doing research.
Introduction The efficacy of high-resolution computed tomography (HRCT) chest in common respiratory infections is well-established; however, its use in the diagnosis of COVID-19 pneumonia is less popular. The previous studies have failed to establish the efficacy of HRCT in the diagnosis of COVID-19 pneumonia. Objective The current study aimed to assess the efficacy of HRCT as compared to a polymerase chain reaction (PCR) in diagnosing COVID-19 pneumonia in patients in our setting. Methodology A prospective observational study was conducted at the Department of Chest Medicine, Shifa International Hospital from April 2020 to December 2020. A total of 250 patients were admitted to medical intensive care units. Findings of HRCT and PCR were documented. The accuracy of HRCT compared with PCR was assessed. Data were analyzed using SPSS version 24 (IBM Corp., Armonk, NY). Results COVID-19 infection was more prevalent in male patients (62.8% vs 37.2%). The mean age was 60 years (interquartile range, IQR, 49-72). Sensitivity and specificity of HRCT segregated into typical, indeterminate, and atypical HRCT were (94.8%, 56.8%), (92.7%, 47.2%), and (91.7%, 76.8%), respectively. The positive predictive value for typical HRCT was 84.3% (p≤0.001). Conclusion We concluded that typical HRCT findings have diagnostic utility in the diagnosis of COVID pneumonia. Similarly, a negative HRCT chest reliably excludes the possibility of COVID pneumonia. HRCT chest is a reliable alternative to RT-PCR.
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